INVASIVE BREAST CANCER

This early-phase study tested a vaccine made from patients' own immune cells to target HER2-positive breast cancer. 31 participants with stage II or III breast cancer received the vaccine alongside standard chemotherapy before surgery. The goal was to see if the vaccine could boo…

This study looked at 720 women with early-stage breast cancer who had a lumpectomy. They were split into two groups: one got standard daily radiation for several weeks, the other got a shorter course of higher-dose radiation. The goal was to see if the shorter treatment works jus…

This study tested a new way to tell breast cancer types apart using a special ultrasound, instead of a tissue biopsy. Researchers looked at blood vessel patterns in tumors from 94 patients and built a tool to predict whether the cancer was luminal or non-luminal. The goal is to h…

This study tested whether a special PET/MRI scan using a tracer called FFNP can accurately measure progesterone receptors in invasive breast cancer. Twenty-one women with breast tumors at least 1 cm in size took part. The goal was to see if the scan results match the standard lab…

This study tested whether EMDR (a therapy using guided eye movements) could help reduce anxiety and depression in women with breast cancer. Fifteen women who had mastectomy for invasive breast cancer received up to 8 sessions of EMDR during their cancer treatment. The main goal w…

This study tested two behavioral programs—coping skills training and general health education—to see which better improves well-being in people with ongoing pain after breast cancer surgery. About 316 participants who had surgery for breast cancer or precancerous conditions took …

This study compared two types of nipple-sparing mastectomy for breast cancer: one done with a robot and the other with traditional open surgery. 82 women took part, and the main goal was to see which approach led to higher patient satisfaction. The trial also looked at recovery t…

This trial tested a new device called the Breast Cancer Locator (BCL), a custom plastic bra that helps surgeons find tumors during breast-conserving surgery. It was compared to the standard wire localization method in 480 women with non-palpable breast cancer. The goal was to see…

This completed study analyzed tissue samples from 108 breast cancer patients to identify proteins linked to early cancer invasion. The goal was to find markers that could help assess the risk of tumor spread in patients without lymph node involvement. Researchers focused on listi…

This study measured levels of a protein called IP3R3 in breast cancer tissue from 42 women. The goal was to see if this protein is involved in how cancer cells migrate and invade nearby tissues. Researchers hope this could lead to better understanding of what makes breast cancer …

This completed study looked at ways to increase diversity in cancer clinical trials, focusing on breast, liver, and prostate cancers. Researchers worked with communities, doctors, and scientists in New York City to find better ways to include people of color and underserved group…

This study looked at whether a special, graph-based genetic counseling method helps newly diagnosed breast cancer patients better understand their risk of cancer in the other breast and make more informed surgery choices. About 400 patients participated, comparing this new approa…

This completed study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers compared different surgery and radiation techniques to see which ones led to less breast hardening (fibrosis) and better cosmetic results. The goal was to find w…

This study looked at how to better educate women with breast cancer about sexual health during treatment. Researchers held focus groups with 93 patients to understand their needs and preferences. The goal was to create educational materials that could improve sexual well-being th…

This study tested a noninvasive imaging method called Diffuse Optical Spectroscopy Imaging (DOSI) to see if it could predict how breast cancer responds to chemotherapy. Twenty-four women with breast cancer were scanned up to 9 times during their treatment. The goal was to see if …

This study looked at the DNA of breast tumors from 140 patients to understand why some cancers are destroyed by standard chemotherapy and others are not. Researchers analyzed genetic changes in the tumors and compared them to normal DNA. The goal is to find new drug targets and i…