Single-Dose radiation during lumpectomy: a new option for early breast cancer?
NCT ID NCT04595435
First seen Jun 25, 2026 · Last updated Jul 24, 2026 · Updated 3 times
Summary
This registry follows 94 women aged 50 and older with early-stage, low-risk breast cancer who received a single dose of radiation directly to the tumor site during lumpectomy (IORT). The goal is to monitor cancer recurrence, side effects, and patient satisfaction over time. Because IORT is newer and still debated, this study will help clarify its real-world outcomes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Intraoperative radiation therapy (IORT) using low-energy X-rays
- What this could lead to
- If successful, this registry could confirm that IORT is a safe and effective alternative to whole-breast radiation for certain early-stage breast cancers, potentially reducing treatment time and side effects.
- What could go wrong
- This is an observational registry, not a controlled trial, so it cannot prove IORT is better than standard radiation. Recurrence rates remain a concern, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical Center, Navicent Health
Macon, Georgia, 31201, United States
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