Single-Dose radiation during lumpectomy: a new option for early breast cancer?

NCT ID NCT04595435

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This registry follows 94 women aged 50 and older with early-stage, low-risk breast cancer who received a single dose of radiation directly to the tumor site during lumpectomy (IORT). The goal is to monitor cancer recurrence, side effects, and patient satisfaction over time. Because IORT is newer and still debated, this study will help clarify its real-world outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Intraoperative radiation therapy (IORT) using low-energy X-rays

What this could lead to

If successful, this registry could confirm that IORT is a safe and effective alternative to whole-breast radiation for certain early-stage breast cancers, potentially reducing treatment time and side effects.

What could go wrong

This is an observational registry, not a controlled trial, so it cannot prove IORT is better than standard radiation. Recurrence rates remain a concern, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EARLY-STAGE BREAST CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm female breast carcinoma invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medical Center, Navicent Health

    Macon, Georgia, 31201, United States