HIGH-GRADE B-CELL LYMPHOMA
Clinical trials for HIGH-GRADE B-CELL LYMPHOMA explained in plain language.
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Scientists test new drug to supercharge Cancer-Fighting CAR-T cells
Disease control TerminatedThis early-stage trial is testing whether adding an experimental drug called E7777 before standard CAR-T cell therapy can improve results for adults with aggressive B-cell lymphomas that have returned or not responded to prior treatments. The drug aims to help the CAR-T cells wor…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated Apr 01, 2026 20:11 UTC
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Scientists test radiation boost to supercharge Cancer-Fighting cells
Disease control OngoingThis study is testing if adding a low dose of radiation therapy is safe and practical for patients before they receive a CAR-T cell treatment for B-cell lymphoma that has returned or not responded to other therapies. The goal is to see if this combination can improve outcomes for…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New drug combo tested in japanese lymphoma patients after other treatments fail
Disease control OngoingThis trial is testing a drug called epcoritamab, alone or combined with standard treatments, for Japanese adults with B-cell lymphomas that have returned or not responded to prior therapy. The first part finds the safest and most effective dose. The second part treats more people…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: Genmab • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New hope for lymphoma patients Who've run out of options
Disease control OngoingThis early-stage study is testing whether adding a new immunotherapy drug called mosunetuzumab to standard chemotherapy is safe and effective for adults with aggressive B-cell lymphoma that has returned or not responded to prior treatment. The trial will enroll 24 participants to…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: Washington University School of Medicine • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Double-Punch combo trial aims to boost Cancer-Killing power
Disease control OngoingThis study is testing whether adding a pill called acalabrutinib makes a powerful cell therapy (CAR-T) work better and safer for people with certain aggressive B-cell lymphomas. The trial enrolled 23 adults to see if the combination is safe and can help control the cancer. Resear…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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Scientists test new arsenal against stubborn blood cancer
Disease control TerminatedThis early-stage study is testing a new combination of three drugs for adults with an aggressive type of lymphoma that has come back or not responded to previous treatments. The main goal is to find the safest and most effective dose of these drugs when used together. Researchers…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Targeted missile drug joins fight against Tough-to-Treat lymphomas
Disease control OngoingThis study is testing whether adding a new targeted drug called polatuzumab vedotin to standard chemotherapy works better for people with aggressive types of B-cell lymphoma. The trial aims to see if this combination helps more patients achieve complete remission and controls the…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: PHASE2 • Sponsor: Barbara Ann Karmanos Cancer Institute • Aim: Disease control
Last updated Mar 10, 2026 12:53 UTC
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Tiny chip in blood could spot cancer return sooner
Knowledge-focused OngoingThis study is testing a new nanochip technology that analyzes blood samples to monitor how well treatment is working and to try to detect if cancer returns earlier in patients with diffuse large B-cell lymphoma. Researchers will collect blood from 73 patients at diagnosis, during…
Matched conditions: HIGH-GRADE B-CELL LYMPHOMA
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC