Lymphoma patients may get a simpler shot option

NCT ID NCT05207670

Ongoing Disease control Sponsor: Genentech, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests a drug called mosunetuzumab, given as a shot under the skin, for people with certain types of non-Hodgkin lymphoma. The study includes 320 participants and aims to see if the drug can shrink tumors or delay cancer growth. Researchers are also checking for side effects like cytokine release syndrome, which can be treated with another drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mosunetuzumab
What this could lead to: If successful, this could provide a more convenient subcutaneous treatment option for certain B-cell lymphomas, potentially improving disease control.
What could go wrong: This is a mid-stage trial with no control group, so results are preliminary. Side effects like cytokine release syndrome (CRS) are possible, and the drug may not work for all lymphoma types studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma mantle cell lymphoma marginal zone lymphoma non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-HODGKIN LYMPHOMA

Contacts and locations

Locations

Alaska Oncology & Hematology, LLC

Anchorage, Alaska, 99508, United States
American Oncology Partners of Maryland, PA

Bethesda, Maryland, 20817-1915, United States
Astera Cancer Care East Brunswick

East Brunswick, New Jersey, 08816, United States
Cancer Specialists of North Florida - Jacksonville

Jacksonville, Florida, 32256, United States
City of Hope

Duarte, California, 91010, United States
Florida Cancer Specialists - EAST - SCRI - PPDS

West Palm Beach, Florida, 33401-3406, United States
Florida Cancer Specialists - NORTH - SCRI - PPDS

St. Petersburg, Florida, 33705-1449, United States
Infirmary Cancer Care

Mobile, Alabama, 36607-3513, United States
Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336-7774, United States
Kaiser Foundation Hospitals

Portland, Oregon, 97227, United States
Mayo Clinic - PPDS

Rochester, Minnesota, 55905, United States
Mayo Clinic Arizona

Phoenix, Arizona, 85054-4504, United States
Mayo Clinic Jacksonville - PPDS

Jacksonville, Florida, 32224-1865, United States
McGlinn Cancer Institute at Reading Hospital

West Reading, Pennsylvania, 19611, United States
Medical Oncology Hematology Consultants

Newark, Delaware, 19713-2055, United States
Mission Blood and Cancer - MercyOne Cancer Center

Des Moines, Iowa, 50314-3030, United States
MultiCare Deaconess Cancer and Blood Specialty Center

Spokane, Washington, 99218-8205, United States
NY Cancer & Blood Specialist

New York, New York, 10028-0506, United States
New York Cancer & Blood Specialists - Bronx

The Bronx, New York, 10469-5930, United States
New York Cancer & Blood Specialists - New Hyde Park

New Hyde Park, New York, 11042-1116, United States
New York Oncology Hematology, P.C.

Albany, New York, 12206, United States
North Shore Hematology Oncology Association PC

Shirley, New York, 11967, United States
Oncology Associates of Oregon, P.C.

Eugene, Oregon, 97401, United States
Oncology Hematology Care - SCRI

Zachary, Louisiana, 70791, United States
Oncology Hematology Care Inc - Cincinnati - USOR

Cincinnati, Ohio, 45236-2725, United States
Providence Cancer Institute

Portland, Oregon, 97213-2933, United States
Rocky Mountain Cancer Centers (Aurora) - USOR

Aurora, Colorado, 80012-5405, United States
SCRI Florida Cancer Specialists South

Fort Myers, Florida, 33916, United States
San Juan Oncology Associates

Farmington, New Mexico, 87401, United States
St. Vincent Frontier Cancer Center

Billings, Montana, 59101, United States
Tennessee Oncology - Nashville

Nashville, Tennessee, 37203, United States
Tennessee Oncology Chattanooga

Chattanooga, Tennessee, 37404-3230, United States
Texas Oncology (Amarillo) - USOR - 1826 Point West Pkwy

Amarillo, Texas, 79124-2167, United States
Texas Oncology (Tyler) - USOR

Tyler, Texas, 75702-8363, United States
Texas Oncology (Worth) - USOR

Dallas, Texas, 75246-2008, United States
Texas Oncology-Austin Midtown

Austin, Texas, 78705, United States
University of Kansas Medical Center

Westwood, Kansas, 66205, United States
VA Puget Sound Health Care System - NAVREF - PPDS

Seattle, Washington, 98108-1532, United States
Virginia Cancer Specialists - Gainsville

Gainesville, Virginia, 20155-3257, United States

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