New CAR-T therapy targets Tough-to-Treat lymphomas

NCT ID NCT06014762

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tests a new treatment called P-CD19CD20-ALLO1 for people with certain types of B-cell blood cancers that have come back or not responded to standard therapy. The treatment uses specially engineered immune cells from a healthy donor to attack cancer cells. The main goal is to check safety and find the best dose in about 120 adults.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma follicular lymphoma high grade B-cell lymphoma interdigitating dendritic cell sarcoma primary mediastinal large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advent Health Orlando

    Orlando, Florida, 32803, United States

  • Baylor Scott & White Research Institute

    Dallas, Texas, 75204, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, 90048, United States

  • Indiana University

    Indianapolis, Indiana, 46202, United States

  • Loma Linda University Cancer Center

    Loma Linda, California, 92354, United States

  • NYU Grossman School of Medicine

    New York, New York, 10016, United States

  • Ochsner Clinic Foundation

    New Orleans, Louisiana, 70121, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • Our Lady of the Lake Hospital

    Baton Rouge, Louisiana, 70808, United States

  • Pennsylvania State University

    Hershey, Pennsylvania, 17033, United States

  • Prisma Health - Upstate Cancer Institute

    Greenville, South Carolina, 29605, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45206, United States

  • University of Oklahoma, Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wayne State - Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States