New CAR-T therapy targets Tough-to-Treat lymphomas
NCT ID NCT06014762
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests a new treatment called P-CD19CD20-ALLO1 for people with certain types of B-cell blood cancers that have come back or not responded to standard therapy. The treatment uses specially engineered immune cells from a healthy donor to attack cancer cells. The main goal is to check safety and find the best dose in about 120 adults.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Advent Health Orlando
Orlando, Florida, 32803, United States
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Baylor Scott & White Research Institute
Dallas, Texas, 75204, United States
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Cedars-Sinai Medical Center
Los Angeles, California, 90048, United States
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Indiana University
Indianapolis, Indiana, 46202, United States
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Loma Linda University Cancer Center
Loma Linda, California, 92354, United States
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NYU Grossman School of Medicine
New York, New York, 10016, United States
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Ochsner Clinic Foundation
New Orleans, Louisiana, 70121, United States
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Oregon Health & Science University
Portland, Oregon, 97239, United States
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Our Lady of the Lake Hospital
Baton Rouge, Louisiana, 70808, United States
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Pennsylvania State University
Hershey, Pennsylvania, 17033, United States
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Prisma Health - Upstate Cancer Institute
Greenville, South Carolina, 29605, United States
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
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University of Cincinnati
Cincinnati, Ohio, 45206, United States
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University of Oklahoma, Health Sciences Center
Oklahoma City, Oklahoma, 73104, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37232, United States
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Wayne State - Karmanos Cancer Institute
Detroit, Michigan, 48201, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a targeted pill boost Chemotherapy's punch against lymphoma?
- Can a simple blood test spot lymphoma earlier?
- Can a Four-Pronged attack beat brain lymphoma?
- What happens years after CAR-T therapy? a study aims to find out
- Can a new drug combo outsmart resistant lymphomas?
- Can a targeted drug boost standard chemo for aggressive lymphoma?