HEALTHY SUBJECTS

This early-stage study tested a new experimental drug called AZD7798 in healthy volunteers and people with Crohn's disease. Researchers wanted to understand the drug's safety, side effects, and how the body processes it. The study involved 112 participants who received either the…

This study tested if a new single pill containing three cholesterol-lowering drugs works the same way in the body as taking the three drugs separately. It involved 58 healthy adult volunteers to compare how the body absorbs and processes the medications. The goal is to see if the…

This early-stage study tested the safety of a new inhaled drug called SHR-4597. It involved 62 healthy volunteers and people with asthma to see how their bodies handled single and multiple doses. The main goal was to check for side effects and understand how the drug moves throug…

This study tested whether a new single pill containing three cholesterol-lowering drugs works the same way in the body as taking the three separate pills together. It involved 58 healthy adult volunteers to compare how the body absorbs and processes the medications. The goal is t…

This study tested a new single pill that combines three cholesterol-lowering medicines. Researchers wanted to see if this one pill gets into the bloodstream the same way as taking the three separate pills together. The study involved 58 healthy adults to compare how the body proc…

This study tested if a new single pill containing three cholesterol-lowering drugs works the same way in the body as taking the three drugs as separate pills. It involved 58 healthy adult volunteers to measure how the body absorbs and processes the medications. The goal is to see…

This study tested a new, long-wear heart monitor patch called the ZywieZ3. Researchers compared its heart signal readings to a standard medical device over one hour, then checked if it stayed comfortable and accurate when worn for 10 days. They also tested how forgiving the patch…

This study tested whether practicing mindfulness meditation could improve quality of life and ease anxiety and depression for people with epilepsy that doesn't respond well to medication. It involved 37 participants, including people with epilepsy and healthy volunteers, who lear…

This was an early safety study of a new injection called AYP-101, designed to reduce fat under the chin. It tested a single dose in 26 healthy adults to see how their bodies processed the drug and to check for side effects. The main goal was to understand the safety and basic beh…

This study tested if a short session of static neck stretching could lower blood pressure in healthy adults. Researchers measured blood pressure, tissue stiffness, and heart rate in 25 participants to see if stretching relaxes blood vessels. The goal was to see if this simple act…

This study tested a new method for preparing and storing platelets, a blood component vital for clotting, to see if they survive and function well in the body after 5 days. Researchers collected platelets from 40 healthy volunteers, treated them with a special system, stored them…

This early-phase study tested how a drug called N-803 affects natural killer immune cells collected from healthy people. Ten healthy volunteers donated blood cells twice—once before and once after receiving an N-803 injection. Researchers measured safety and compared how the drug…

This study aimed to see if two different versions of a drug (DWJ1445 and DWC202506) behave the same way in the body. It involved 70 healthy adults who each took both drugs at different times. Researchers measured drug levels in the blood to compare them and checked for safety.

This study tested different skin adhesives used to attach a small medical recorder behind the ear. Researchers enrolled 34 healthy adults to see how gentle the adhesives were on skin over time. The main goal was to check for skin irritation and ensure the adhesives were safe and …

This was an early-stage study to check the safety of a new oral drug called SUL-238 and see how the body processes it. It involved 83 healthy adults aged 40 and over. Researchers tested different single and repeated doses to find the highest safe amount and measured drug levels i…

This study aimed to improve the quality and accuracy of MRI scans used in hospitals. Researchers tested different scanning settings on 1,807 healthy volunteers to find the best methods for imaging the brain, heart, and other body areas. The goal was to help doctors get clearer, m…

This completed study aimed to understand how a specific type of immune cell, called myeloid-derived suppressor cells (MDSCs), contributes to the chronic inflammation and blood vessel growth seen in primary myelofibrosis, a serious bone marrow cancer. Researchers studied blood and…

This was the first study in people to check the safety and how the body processes a new drug called TISA-818. It involved 49 healthy adults who received either the drug or a placebo injection. The main goal was to see what side effects might occur and how long the drug stays in t…

This early-stage study tested the safety and how the body processes a new drug called ABSK061 in healthy adults. Researchers gave single and multiple doses of the tablets to 40 volunteers to check for side effects and see how food affects absorption. The goal was to gather basic …

This early-stage study tested how two new drugs, VNRX-7145 and VNRX-5024, interact when taken together and measured their safety in healthy adults. The goal was to understand how the body processes these drugs and what side effects might occur. This information helps researchers …

This was the first study in humans for an experimental drug called CKD-508. It tested the safety and how the body processes the drug in 44 healthy adults. The main goal was to see if the drug was safe and to measure its levels in the blood, while also checking for early signs of …

This study tested whether new computer processing methods could create higher-resolution, more detailed images from regular CT scans. Researchers enrolled 148 adults who were already scheduled for CT scans for heart or lung conditions. They compared the standard CT images with en…

This study aimed to create a detailed photo guide to help doctors assess skin aging. Researchers enrolled 250 healthy women, aged 20-75, to take special photos and use a non-invasive scanner to measure collagen in their skin. The goal was to understand the relationship between ag…

This was a first-in-human study to check the safety and see how the body processes a new drug called LV232. It involved 81 healthy Chinese volunteers who received a single dose of either the drug or a placebo. The main goal was to see how safe the drug is and to measure its level…

This study tested whether a special lecture on the neuroscience of pain could change how physical therapy students think about and approach patients with chronic pain. 120 students in Jordan were randomly assigned to either receive this special pain science lecture or a standard …

This was the first study in humans to test the safety and body's response to a new drug called SAR441255. It involved 48 healthy to slightly overweight adults who received a single injection. The main goal was to see if it was safe and to measure how it affected blood sugar and i…

This study aimed to understand how our body's natural daily rhythms affect measurements of immune system age. Researchers tested 50 healthy adults aged 20-69 at three different times during the same day. They measured a biomarker called IMMAX to see if immune age readings change …

This was an early-stage study to check the safety and see how the body processes a new experimental capsule called TJ0113. It involved 130 healthy adult volunteers who took single or multiple doses of the capsule or a placebo. The main goal was to see if the capsule was safe and …

This early-stage study tested the safety of an experimental drug called M6229 in 15 healthy volunteers. Participants received the drug through a continuous 120-hour (5-day) IV infusion at different dose levels. The main goal was to check for side effects and understand how the bo…

This early-stage study aimed to check the safety and see how the body absorbs and processes an experimental drug called VNRX-5024. It involved 36 healthy adult volunteers who took either the drug or a placebo for up to 10 days. The main goal was to find a safe dose range and unde…

This was the first study in people to check the safety and how the body processes a new drug called UP-818-CC. It involved 73 healthy Chinese volunteers who received either the drug or a placebo. The main goal was to see what side effects occurred and to measure how long the drug…

This study aimed to find out if vocal exercises (like singing techniques) or traditional breathing exercises are better for improving lung function and core stability in healthy women. Fifty women aged 18-65 were randomly assigned to follow a 6-week program of either vocal or bre…

This early-stage study tested a new drug called cenerimod in 97 healthy people. The main goal was to see if cenerimod affects the heart's electrical rhythm (QT interval). Researchers also checked if cenerimod changes how birth control pills work in the body and tested a method to…

This study aimed to see if pea protein works as well as the popular whey protein for helping people build muscle and strength. Thirty-four healthy young adults who were not regular exercisers took either pea or whey protein twice a day while doing a supervised weight training pro…

This early-stage study aimed to understand the safety and how the body processes a new capsule called LV232. It involved 49 healthy volunteers to test different doses and see if eating food changes how the capsule is absorbed. The main goal was to gather basic safety and absorpti…

This study aimed to see if a new insulin called Insulex R works similarly in the body to a widely used insulin called Humulin R. It involved 40 healthy adults who each received a single dose of both insulins in a carefully controlled setting. The main goal was to measure how the …

This study aimed to see if doing squats on an unstable surface (like a wobble board) gives a better immediate boost to balance and coordination than doing them on solid ground. Researchers tested 42 healthy, young adults, having them perform 30 squats under both conditions to mea…

This study aimed to understand the genetic factors behind Combined Pulmonary Fibrosis and Emphysema (CPFE), a severe lung disease mostly affecting smokers. Researchers compared 250 people, including patients with CPFE, other lung conditions, and healthy individuals, to see if tho…

This study aimed to understand how the body processes and eliminates an experimental drug called cenerimod. Six healthy male volunteers took a single dose containing a tiny, safe amount of radioactive tracer. Researchers then carefully measured how much of the drug left the body …

This study aimed to understand how two common anxiety medications (diazepam and lorazepam) affect brain activity during different types of memory tasks. Researchers gave single doses to 22 healthy young volunteers and used brain scans (fMRI) to see how the drugs changed brain pat…

This study used advanced brain imaging (PET scans) to see how the frontal lobe works during thinking tasks. It compared healthy volunteers to people with conditions like schizophrenia and Parkinson's disease to understand brain function differences. The goal was to gather knowled…

This research study aimed to understand how the brain's frontal lobe works during thinking tasks like categorization and analogical reasoning. Researchers compared brain activity in 130 participants—some with frontal dementia conditions and some healthy volunteers—using cognitive…

This early-stage study aimed to check if multiple doses of an experimental drug called zidebactam are safe for healthy people and to see how the body processes it. The drug is being developed to help fight tough bacterial infections. A small group of 21 healthy adults received ei…

This early study tested a new radioactive tracer used in PET brain scans to measure serotonin 1A receptors, which are involved in mood and neurological function. It involved 20 healthy volunteers who underwent brain scans to see how well the tracer worked and if measurements were…

This study aimed to understand if simple neck exercises could improve flexibility in other parts of the body. Researchers tested 30 healthy young adults to see if stretching or using a massage roller on the neck could increase the range of motion not just in the neck, but also in…

This study aimed to understand how the body processes and tolerates multiple doses of a 7.5mg tolvaptan tablet. It involved 12 healthy male volunteers to measure drug levels in the blood and check for side effects. The goal was to gather basic safety and drug-handling information…

This study aimed to see if two different versions of the same antibiotic combination (amoxicillin & clavulanic acid) are absorbed by the body in the same way. It involved 63 healthy volunteers who each took both versions in a specific order. Researchers measured drug levels in th…