HEALTHY SUBJECTS

This study tested whether a short session of static neck stretching can lower blood pressure in healthy adults. 25 volunteers participated, and researchers measured blood pressure, tissue stiffness, and heart rate before and after stretching. The goal was to see if stretching rel…

This study looked at whether practicing mindfulness meditation can help people with epilepsy that doesn't get better with medication. 37 people took part, including those with epilepsy and healthy volunteers. The goal was to see if meditation improves quality of life and changes …

This early-stage study tested a new inhaler medicine called SHR-4597 in 62 people—some healthy and some with asthma. The main goal was to see if it is safe and tolerable. Researchers gave single doses to healthy volunteers and multiple doses over 16 days to asthma patients, monit…

This early-stage study tested a single injection of AYP-101 in 26 healthy adults to see if it is safe and how the body handles it. The injection targets fat under the chin. The main goal was to check for side effects, not to measure how well it reduces fat.

This study looked at how a drug called cenerimod leaves the body. Six healthy men aged 45 to 65 took a single dose with a radioactive tag. Researchers measured the drug's breakdown and removal in urine, feces, and breath to understand its metabolism.

This study checked whether a new version of an amoxicillin/clavulanic acid drug (YHP2406) works the same as the original (YHR2501) in 63 healthy adults. Each person took a single dose of both drugs at different times, and researchers measured drug levels in the blood. The goal wa…

This study tested whether doing 30 squats on an unstable surface (like a wobble board) improves balance and coordination more than squats on a stable floor. 42 healthy adults aged 18-35 participated. Researchers measured postural stability, leg coordination, and dynamic balance r…

This study checked if a new wearable ECG sensor (ZywieZ3) works as well as standard hospital monitors. 45 healthy adults wore the device for up to 10 days while doing normal activities. Researchers compared the sensor's heart recordings to a traditional ECG and tested how well th…

This early-stage study tested a new drug called MT-7117 in 40 healthy Chinese adults to see how safe it is and how the body processes it. Participants received either the drug or a placebo, and researchers measured drug levels in the blood and monitored for side effects. This stu…

This early-stage study tested a new drug called UP-818-CC in 73 healthy Chinese volunteers to see if it is safe and how the body processes it. Participants received either the drug or a placebo as a single dose or daily doses for a week. The main goal was to check for side effect…

This study looked at how the drug cenerimod affects heart electrical activity (QT interval), how it interacts with birth control pills, and how charcoal changes its absorption. 97 healthy adults took part. The goal was to gather safety and drug interaction information, not to tre…

This study looked at the genetics of a rare lung condition called combined pulmonary fibrosis and emphysema (CPFE), which causes severe breathing problems mostly in smokers. Researchers compared 250 people with CPFE, other lung diseases, or healthy lungs to see if those with CPFE…

This study looked at how two anxiety medications, lorazepam and diazepam, affect memory and brain activity in 22 healthy young adults. Participants took a single dose of one drug and then performed memory tasks while their brains were scanned using fMRI. The goal was to understan…

This study looked at 70 people—some with primary myelofibrosis (a rare bone marrow disorder) and some healthy—to understand how certain immune cells called MDSCs fuel inflammation and blood vessel growth in the disease. Researchers measured these cells in blood and spleen samples…

This early-stage study tested the safety and how the body handles a new drug called LV232. It involved 81 healthy Chinese volunteers who received either the drug or a placebo. The goal was to check for side effects and measure drug levels in the blood, not to treat any disease.

This completed study used PET scans to watch brain activity while people performed thinking tasks. It included healthy volunteers and people with schizophrenia or Parkinson's disease. The goal was to learn how the frontal lobe works during thinking and how certain drugs might aff…

This study looked at how the front part of the brain helps with reasoning and categorizing things. Researchers compared healthy volunteers to people with frontotemporal dementia or progressive supranuclear palsy. They used tasks, brain scans, and magnetic stimulation to understan…

This early-stage study tested the safety and tolerability of a new drug called TISA-818 in 49 healthy adults. Participants received either the drug or a placebo as a single or multiple daily injections. The goal was to check for side effects and how the drug moves through the bod…

This study looked at whether vocal exercises or breathing exercises work better to improve lung function and trunk (core) stability in healthy women aged 18 to 65. Fifty women did either vocal or breathing exercises twice a week for six weeks. Researchers measured their lung capa…

This study tested a new radioactive tracer called [18F]-F13640 to see how well it can image certain brain receptors (5-HT1A) using PET scans. Twenty healthy volunteers took part to check how the tracer moves in the body and if the results are repeatable. The goal was to improve b…

This study tested a new drug called CKD-508 in 44 healthy adults to see if it is safe and how the body handles it. Participants took the drug or a placebo once daily. The main goals were to check for side effects and measure drug levels in the blood.

This early-stage study tested the safety and how the body processes a new drug called ABSK061 in 40 healthy adults aged 18 to 45. Participants took the drug as minitablets, and researchers measured drug levels in the blood and monitored for side effects. The goal was to gather ba…

This study aimed to make MRI scans clearer and more reliable. Researchers tested new imaging methods on 1,807 healthy adults to improve picture quality and reduce blurring. No treatment or medication was given—the goal was simply to advance imaging technology.

This study looked at whether a special class on the science of pain could change how physical therapy students think about and treat pain. 120 healthy students in Jordan took part. The goal was to see if their knowledge, attitudes, and beliefs about pain improved after the class.

This early-stage study tested the safety of a new drug, SUL-238, in 83 healthy adults aged 40 and older. Participants received either the drug or a placebo, and researchers monitored side effects, lab results, and how the drug moved through the body. The goal was simply to see if…

This study tested the safety and how the body handles a new drug called LV232 in 49 healthy Chinese volunteers. Participants took multiple doses of the drug, and researchers measured how it moved through the body and checked for side effects. This is an early-stage study with no …

This study aimed to see if a new insulin called Insulex R works similarly in the body to an already approved insulin, Humulin R. It involved 40 healthy adults who each received a single dose of both insulins in a random order. Researchers carefully measured how the body absorbed …

This study tested a new drug called AZD7798 in 112 healthy volunteers and people with Crohn's disease. The main goal was to check if the drug is safe and how the body processes it. No treatment effects were measured, so this is an early safety-only study.

This completed Phase 1 trial enrolled 6 healthy men to find out how much of the drug cenerimod enters the bloodstream after taking a pill. Participants took one tablet, then received a tiny radioactive version of the drug through an IV to track it. The study lasted about 3 months…

This early-stage study tested the safety of a new drug, M6229, in 15 healthy adults. Participants received the drug or a placebo as a continuous infusion over 5 days. The goal was to check for side effects and how the body processes the drug, not to treat any disease.

This early-phase study tested the safety and tolerability of a new drug called ICP-332 in 24 healthy adults aged 18 to 55. Participants received either the drug or a placebo, and researchers monitored for side effects and changes in vital signs, lab values, and heart activity. Th…

This early-stage study tested an experimental antibiotic called zidebactam in 21 healthy adults. The goal was to check if multiple doses given through a vein are safe and how the body processes the drug. No treatment was given for any disease, so this study helps gather basic saf…

This study tested whether a single pill containing three cholesterol-lowering medications (bempedoic acid, ezetimibe, and atorvastatin) works the same as taking the three drugs separately. It involved 58 healthy adults aged 18 to 60. The goal was to see if the combination pill is…

This study looked at whether stretching or massaging the neck can also improve flexibility in the hip. Thirty healthy adults received both a neck stretch and a neck massage on separate days. Researchers measured neck and hip movement before and after each treatment to see if ther…

This study looked at whether a single pill containing three cholesterol-lowering medicines (bempedoic acid, ezetimibe, and rosuvastatin) works the same as taking those three medicines separately. It involved 58 healthy adults and measured how the drugs were absorbed and processed…

This early-stage study looked at how safe two experimental antibiotics, VNRX-7145 and ceftibuten, are when given alone or together. Fifty-three healthy adults aged 18 to 55 took part. The goal was to measure how the drugs move through the body and check for side effects, not to t…

This early-stage study tested the safety of an experimental drug called VNRX-5024 in 36 healthy adults aged 18 to 55. Participants received either a single dose or multiple doses over 10 days, and researchers monitored for side effects and how the drug moved through the body. The…

This study tested whether new computer methods can create higher resolution images from regular CT scans. 148 adults who already needed a CT scan took part. Researchers compared the standard images with new, sharper versions made from the same scan data to see if they provide mor…

This study involved 250 healthy women aged 20 to 75 to create a photographic atlas of skin aging. Researchers used a special camera (LC-OCT) to measure collagen in the skin without any needles or surgery. The goal was to better understand how age and sun exposure affect the skin'…

This study looked at whether pea protein powder works as well as whey protein for building muscle and strength in healthy young adults. 34 people took either pea or whey protein twice a day for 8 weeks while doing a weight training program twice a week. Researchers measured chang…

This early-phase study looked at how a drug called N-803 affects natural killer (NK) cells collected from 10 healthy volunteers. The main goal was to check safety and see if N-803 helps NK cells grow and multiply. The study is complete and focused on understanding the process, no…

This early-stage study tested a single dose of an experimental drug called SAR441255 in 48 healthy adults who were lean to overweight. The main goal was to see if the drug is safe and how the body processes it. Researchers also looked at its effects on blood sugar and insulin lev…

This study checked whether two drugs, DWJ1445 and DWC202506, are absorbed and processed by the body in the same way. It involved 70 healthy adults who took a single dose of each drug at different times. The goal was to measure drug levels in the blood, not to treat any disease.

This study looked at whether platelets (blood cells that help clotting) treated with a special light-based system can survive in the body after being stored for 5 days. Healthy adults donated their own platelets, which were treated and then given back to them. The goal was to mea…

This study checked if a single pill containing three cholesterol-lowering medicines (bempedoic acid, ezetimibe, and atorvastatin) works the same in the body as taking them separately. It involved 58 healthy adults aged 18 to 60. The goal was to see if the combination pill is a go…

This study tested whether special adhesive baseplates for the UNEEG Episight recorder are safe and gentle on the skin. Thirty-four healthy adults wore the baseplates behind their ears, and researchers measured skin moisture loss and checked for reactions. The goal was to see if t…

This early-stage study tested TJ0113 capsules in 130 healthy adults to see if they are safe and how the body processes them. Participants took single or multiple doses, and some took the drug after a high-fat meal. The main goal was to track any side effects and measure drug leve…

This study checked whether the time of day changes a person's 'immune age' — a score that shows how well the immune system is working. Researchers took blood from 50 healthy adults (ages 20-69) at 8 a.m., 1 p.m., and 6 p.m. on the same day. The goal was to see if the immune age s…

This study tested the drug tolvaptan in 12 healthy men to see how the body absorbs, processes, and removes it. Researchers also checked for side effects. The goal was to gather safety and drug-level information, not to treat any disease.

This study tested whether a single pill containing three cholesterol-lowering medicines (bempedoic acid, ezetimibe, and rosuvastatin) works the same as taking them separately. It involved 58 healthy adults aged 18 to 60. The goal was to see if the combination pill is absorbed and…