HEALTHY SUBJECTS

This study tests a special education program for first-time mothers that combines hypnosis techniques with breastfeeding information. The goal is to see if it helps mothers feel more confident and motivated to breastfeed. About 80 healthy pregnant women will take part, and resear…

This study explores how alcohol affects the gut microbiome and whether personalized prebiotics can help restore balance. Researchers will test a new tool (DynaMAP) to map gut bacteria in 20 healthy adults who drink moderately. Participants take a daily prebiotic for 60 days, and …

This study tests whether a mild electrical current applied to the ear can activate the vagus nerve, which controls stomach function. Thirty healthy volunteers will receive ear stimulation and perform simple maneuvers like coughing. Researchers will measure nerve activity and stom…

This study compares 16 people with mild-to-moderate COPD to 16 healthy volunteers matched by age, sex, and height. Researchers measure blood volume in the lungs and the whole body to see if a smaller lung blood volume contributes to exercise problems. No treatment is given—the go…

This study looks at how exercise training changes the way muscles process fat and sugar, which is linked to insulin resistance and type 2 diabetes. Researchers will study healthy, lean, and overweight participants before and after a 16-week running or yoga program. The goal is to…

This study looks at how the drug rifampicin changes the way another drug, HSK31858, is processed in the body. It involves 24 healthy adults aged 18 to 45. The goal is to measure drug levels in the blood, not to treat any disease.

This study looks at how a common antifungal drug, itraconazole, changes the way the body handles an experimental drug called HSK31858. It involves 24 healthy adults aged 18 to 45. Participants will take both drugs in a fixed order, and researchers will measure drug levels in the …

This early-phase trial at Massachusetts General Hospital is studying how the body processes high doses of inhaled nitric oxide in 10 healthy adults aged 18–64. Participants breathe the gas for 30 minutes, three times a day, while researchers measure methemoglobin levels—a byprodu…

This study looks at how eating salt changes the way our genes control blood pressure. Researchers will test 88 healthy adults aged 25-45 to see how their bodies respond to salt and a hormone called angiotensin II. The goal is to understand why some people are more sensitive to sa…

This study tests whether non-invasive brain stimulation (rTMS) can alter gut activity in healthy people and those with functional dyspepsia or IBS. Researchers will measure stomach rhythms, heart rate, and fullness thresholds after applying rTMS to the motor cortex. It is an earl…