Brain scans reveal how common sedatives alter memory
NCT ID NCT00696033
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This completed study gave 22 healthy volunteers a single dose of diazepam, lorazepam, or a placebo, then used brain scans to see how these drugs affect memory and perception. The goal was to understand why lorazepam may impair unconscious memory more than diazepam. The findings could help doctors use these medications more safely.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
diazepam and lorazepam (single oral doses)
What this could lead to
If successful, this could help explain how benzodiazepines affect memory and perception, guiding safer use of these drugs.
What could go wrong
This is a small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world medical use or predict long-term effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Centre d'investigation clinique, hôpital civil
Strasbourg, 67091, France
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Clinique psychiatrique, hôpital civil
Strasbourg, 67091, France