Brain scans reveal how common sedatives alter memory

NCT ID NCT00696033

Completed Knowledge-focused Sponsor: University Hospital, Strasbourg, France Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed study gave 22 healthy volunteers a single dose of diazepam, lorazepam, or a placebo, then used brain scans to see how these drugs affect memory and perception. The goal was to understand why lorazepam may impair unconscious memory more than diazepam. The findings could help doctors use these medications more safely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: diazepam and lorazepam (single oral doses)
What this could lead to: If successful, this could help explain how benzodiazepines affect memory and perception, guiding safer use of these drugs.
What could go wrong: This is a small, early-phase study in healthy volunteers, not patients. Results may not apply to real-world medical use or predict long-term effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEALTHY SUBJECTS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY SUBJECTS

Contacts and locations

Locations

Centre d'investigation clinique, hôpital civil

Strasbourg, 67091, France
Clinique psychiatrique, hôpital civil

Strasbourg, 67091, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.