PET scans reveal how the brain thinks in health and disease
NCT ID NCT00001258
First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 10 times
Summary
This study used PET scans to measure blood flow in the frontal lobe while participants performed thinking tasks. It included healthy volunteers and people with schizophrenia or Parkinson's disease. The goal was to understand how the frontal lobe works during cognitive activities and how drugs might affect it.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Oxygen-15 water
- What this could lead to
- If successful, this could help researchers understand how the frontal lobe works in thinking and how it is affected in neuropsychiatric disorders.
- What could go wrong
- This is an observational imaging study, not a treatment trial. It may not lead directly to new therapies or change patient care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
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