Scientists hunt for genetic clues in rare lung syndrome

NCT ID NCT02439528

First seen Jan 04, 2026 · Last updated May 15, 2026 · Updated 17 times

Summary

This study looked at 250 people to understand why some smokers develop a rare combination of lung scarring and emphysema (CPFE syndrome). Researchers compared telomere length and genetic mutations in patients with CPFE, those with only scarring or only emphysema, and healthy volunteers. The goal was to find genetic differences that might explain the syndrome, but this was an observational study, not a treatment trial.

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Contacts and locations

Locations

  • Hôpital Albert Michallon, CHU de Grenoble

    Grenoble, 38 043, France

  • Hôpital Nord, CHU de Saint-Etienne

    Saint-Etienne, 42055, France

  • Hôpital pneumologique et cardiovasculaire Louis Pradel, HCL

    Bron, 69677, France

Conditions

Explore the condition pages connected to this study.