Scientists hunt for genetic clues in rare lung syndrome

NCT ID NCT02439528

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 250 people to understand why some smokers develop a rare lung condition called combined pulmonary fibrosis and emphysema (CPFE). Researchers compared telomere length and genetic mutations in patients with CPFE, those with only fibrosis or emphysema, and healthy individuals. The goal was to find genetic differences that might explain why some people get this severe disease.

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Conditions

The condition(s) this trial relates to.

combined pulmonary fibrosis-emphysema syndrome idiopathic pulmonary fibrosis pulmonary emphysema pulmonary fibrosis syndromic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital Albert Michallon, CHU de Grenoble

    Grenoble, 38 043, France

  • Hôpital Nord, CHU de Saint-Etienne

    Saint-Etienne, 42055, France

  • Hôpital pneumologique et cardiovasculaire Louis Pradel, HCL

    Bron, 69677, France