EMPHYSEMA

This study tests a new device called the IAB 50 Flex, an implantable artificial bronchus for adults with severe COPD or emphysema. The trial will enroll 20 participants across two hospitals to check if the implant is safe and if it helps improve breathing and daily activity. The …

This study tests a new device called an implantable artificial bronchus (IAB) for people with severe emphysema or COPD. The IAB is designed to help air move in and out of the lungs more easily. About 60 adults will receive the implant and be followed for 90 days to see if it impr…

This study tests a permanent implant called the Apreo BREATHE Airway Scaffold in up to 250 adults with COPD and emphysema who still feel short of breath despite standard treatments. The implant is designed to prop open airways and release trapped air to improve breathing. Researc…

This study tests a specialized clinic designed to diagnose and treat muscle loss (sarcopenia) in people with COPD. The clinic brings together a team of experts to provide targeted care. Researchers will see if this approach improves muscle mass and function, and reduces hospitali…

This study is testing a new ultrasound measurement called the Lung Sliding Index (LSI) to see if it can help doctors tell apart different lung diseases, such as COPD, pneumonia, and pulmonary edema. Researchers will measure LSI in 700 adults with various lung conditions and healt…

This registry study is tracking 150 adults with severe emphysema who receive the Spiration Valve System, a one-way valve placed in the lung via a bronchoscope. The goal is to see if the device safely reduces shortness of breath and lung overinflation over 12 to 36 months. Partici…

This study looks at whether lung ultrasound can detect emphysema (a type of lung damage) as well as CT scans do. About 1,600 people with or without emphysema will get both an ultrasound and a CT scan. The goal is to find patterns on ultrasound that match the damage seen on CT, wh…

This study examines how a minimally invasive lung valve treatment changes leg muscle function in people with severe emphysema. Researchers will use MRI scans and small muscle samples to measure energy use and muscle structure before and after treatment. The goal is to understand …

This study is creating a registry of people with emphysema to collect DNA, lung function tests, and medical information. Researchers hope to use this data to better understand the disease and develop new therapies. The registry will also help identify volunteers for future resear…