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AI model could predict who needs a lung transplant for rare emphysema

NCT ID NCT07715617

Recruiting now Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study aims to create a prediction tool for people with emphysema caused by alpha-1-antitrypsin deficiency, a rare genetic disorder. Researchers will analyze clinical data, lab results, and lung CT scans from 230 patients to identify those at highest risk of death or needing a lung transplant within five years. The goal is to help doctors personalize care and avoid unnecessary treatments for low-risk patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this prediction tool could help doctors identify which patients need a lung transplant or intensive care sooner, and spare low-risk patients from unnecessary treatments.
What could go wrong
The model is based on past patient data and may not work perfectly for all individuals. It is still in development and needs validation before it can be used in clinics.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alpha 1-antitrypsin deficiency pulmonary emphysema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALPHA 1 ANTITRYPSIN DEFICIENCY ARTIFICIAL INTELLIGENCE (AI) EMPHYSEMA LUNG TRANSPLANTATION MORTALITY PREDICTION PREDICTIVE LEARNING MODELS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bordeaux University Hospital

    RECRUITING

    Pessac, 33600, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • CHU de Lille

    RECRUITING

    Lille, 59000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hospices Civils de Lyon

    RECRUITING

    Bron, 69677, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Hôpital BICHAT CLAUDE-BERNARD

    RECRUITING

    Paris, 75018, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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