ARTIFICIAL INTELLIGENCE (AI)

This study tests whether an artificial intelligence (AI) smartphone app can help people with type 2 diabetes control their blood sugar better than regular doctor visits. About 400 adults will either use the AI app to get personalized diet, exercise, and medication advice, or rece…

This study will enroll 690 adults who come to the emergency room with chest pain (not from injury). Researchers will test whether two AI models, GPT-4o and Claude, can correctly calculate a heart risk score (HEART score) from patient notes and predict if a serious heart event wil…

This study compares how well artificial intelligence (AI) software can analyze dental X-rays compared to a human expert. Researchers will use 100 digital X-rays and have both an orthodontist and three different AI programs measure key angles and distances in the jaw and teeth. Th…

This study tests whether an AI tool can help radiologists diagnose common diseases from medical scans like CT or MRI. About 1,000 patients' images will be reviewed by radiologists with and without AI assistance. The goal is to see if AI improves accuracy, speed, and report qualit…

This study tests an AI tool called EndoAIM that helps doctors measure the size of polyps found during a colonoscopy. Accurate size measurement is important because larger polyps (over 10 mm) have a higher risk of becoming cancer. The study will enroll 278 adults undergoing colono…

This study compares two ways of reading mammograms for breast cancer screening. The standard method uses two radiologists to review each image. The new method uses one radiologist with the help of artificial intelligence (AI). The goal is to see if the AI-assisted single reading …

This study is testing an artificial intelligence system that helps doctors find precancerous polyps (called adenomas) in the colon during a colonoscopy. The AI analyzes images from a special scope to predict which polyps are dangerous. Researchers will enroll 4,000 adults to see …

This study tests whether an artificial intelligence-enhanced electrocardiogram (AI-ECG) can detect pulmonary hypertension—a serious condition where blood pressure in the lungs is dangerously high—in people aged 50 to 85 who are at risk. Over 8,600 participants will get the AI-ECG…

This trial is testing whether an artificial intelligence-enhanced electrocardiogram (AI-ECG) can better identify patients who need a cardiac implantable electronic device (like a pacemaker or defibrillator) compared to standard care. Over 11,000 participants will be randomly assi…

This large trial compares standard mammogram reading by radiologists to reading with the help of an FDA-approved AI tool. The goal is to see if AI improves cancer detection and reduces unnecessary callbacks. About 400,000 adult women across six U.S. health systems will participat…

This study tests whether an artificial intelligence (AI) system can help doctors spot hidden atrial fibrillation (AF) — a common heart rhythm disorder that raises stroke risk — by flagging suspicious electrocardiograms (ECGs). About 14,700 patients will be randomly assigned to ha…

This study tests whether adding an AI app to standard behavioral parent training helps families with children aged 5-12 who have disruptive behaviors like irritability or ADHD. Forty parents will either attend 8 weekly online training sessions alone or with 24/7 access to an AI v…

This study asks 150 surgical nurses about their thoughts on artificial intelligence in their daily work. Researchers want to know if nurses feel ready for AI and how they think it might change patient care. The study does not test any treatment or device—it simply gathers opinion…

This study aims to create a computer model that can predict how soon patients will walk on their own after hip or knee replacement surgery. Researchers will collect data from about 943 patients who had surgery and physical therapy. The goal is to help doctors plan better care, bu…

This study compares a multilingual AI chatbot (PEAR) with standard face-to-face verbal consent for explaining anesthesia risks. About 120 adults having elective surgery will participate. The goal is to see if the chatbot improves patient understanding and reduces anxiety.

This study tests whether using artificial intelligence to read electrocardiograms (ECGs) helps doctors diagnose and treat a severe type of heart attack (occlusion myocardial infarction) more quickly. About 212,000 emergency room patients will be involved, and the study will also …

This study looks at whether using artificial intelligence to simplify medical handouts helps parents understand their child's bone condition better. About 80 parents of children treated at a special surgery hospital will read either the original or an AI-simplified version and th…

This study is collecting short video and voice recordings from 200 cancer patients—some in pain, some not—to create a secure database. The goal is to provide raw material for future artificial intelligence tools that could automatically assess pain from facial expressions and spe…

This study tests an artificial intelligence system called SEASCAPE that helps doctors manage pain during surgery. The AI monitors patient data in real time and suggests the best dose of a painkiller (remifentanil) to avoid giving too much or too little. 150 adults having planned …

This study is testing whether a mobile app called 'Iskhaa' can help brain tumor patients perform their own neurological exams at home. Six hundred participants will use the app to record videos of tasks like speaking and walking, which an AI will analyze. The goal is to see if th…

This study is testing whether an artificial intelligence (AI) tool can help people undergoing IVF treatment stay engaged and follow their doctor's recommendations. Researchers will enroll 774 infertility patients aged 18-45 in Portugal. The goal is to see if personalized AI guida…

This study is creating an artificial intelligence (AI) model that uses MRI scans and tissue samples to predict whether high-risk prostate cancer has spread to nearby lymph nodes. The goal is to help doctors make better treatment decisions without needing extra invasive tests. Abo…

This study surveys 250 people from different age groups (youth, working-age adults, and seniors) to understand what helps or hinders their trust in using artificial intelligence and digital tools in healthcare. The goal is to identify common concerns and effective solutions so th…

This study explores whether using a large language model AI (like ChatGPT) can improve the clinical reasoning skills of physical therapy students. Researchers will compare students who practice with the AI on realistic patient cases to those who follow the standard curriculum. Th…

This study looks at how well an AI system called Patchs helps GP practices triage patients. Researchers will analyze data from over 226,000 patients across England to see if the AI is accurate and treats everyone fairly. The goal is to improve the AI so patients get the right car…

This study tests whether artificial intelligence can evaluate how well surgeons perform a key step in heart bypass surgery. Researchers will compare AI scores to those from human experts. The trial involves 284 patients undergoing bypass grafting and aims to see if AI can reliabl…