AI takes on heart risk: GPT-4o and claude face off against doctors in chest pain study

NCT ID NCT07626060

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will enroll 690 adults who come to the emergency room with chest pain (not from injury). Researchers will test whether two AI models, GPT-4o and Claude, can correctly calculate a heart risk score (HEART score) from patient notes and predict if a serious heart event will happen within 30 days. The AI's performance will be compared to a consensus score from three emergency medicine doctors. The goal is to see if AI can help speed up and improve heart risk assessment in busy ERs.

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Conditions

The condition(s) this trial relates to.

Emergencies

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Marmara University Pendik Training and Research Hospital

    RECRUITING

    Istanbul, Istanbul, 34870, Turkey (Türkiye)

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Other studies related to the condition(s) this trial covers.