Scientists uncover immune cell clues in rare bone marrow disease

NCT ID NCT07319026

First seen Jan 11, 2026 · Last updated May 16, 2026 · Updated 15 times

Summary

This study looked at 70 people—some with primary myelofibrosis (a rare bone marrow disorder) and some healthy—to understand how certain immune cells called MDSCs fuel inflammation and blood vessel growth in the disease. Researchers measured these cells in blood and spleen samples and checked how they change with treatment. The goal is to find new targets for future therapies.

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Contacts and locations

Locations

  • Fondazione IRCCS Policlinico San Matteo di Pavia

    Pavia, Italy, 27100, Italy

Conditions

Explore the condition pages connected to this study.