Could a single pill replace three for cholesterol?

NCT ID NCT07235189

Completed Knowledge-focused Sponsor: Daiichi Sankyo Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a single pill containing three cholesterol-lowering drugs (bempedoic acid, ezetimibe, and atorvastatin) works the same as taking them separately. 58 healthy adults participated in a crossover trial where they received both forms. The goal was to see if the combination pill is absorbed similarly, which could simplify treatment and improve adherence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bempedoic acid, ezetimibe, and atorvastatin
What this could lead to: If successful, this could lead to a simpler, single-pill option for lowering cholesterol, making it easier for patients to stick with their treatment.
What could go wrong: This is an early-stage trial in healthy volunteers, not patients. It only checks if the combination pill is absorbed similarly, not whether it improves health outcomes or is safe long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEALTHY SUBJECTS

Contacts and locations

Locations

Research Site

Porto, 4250-449, Portugal

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