DRY EYE

This study tested whether a new dynamic color temperature mode on screens can prevent dry eye and visual fatigue. Thirty adults read text on a screen for 50 minutes under different color settings. Researchers measured eye fatigue and dryness before and after to see if the new mod…

This early study tested a dexamethasone eye insert placed by a doctor against a standard steroid gel for treating allergy and dry eye symptoms in 36 people with keratoconus who wear gas permeable contact lenses. The goal was to see if the insert improves signs like eyelid bumps a…

This early study tests whether RCI001 eye drops are safe and tolerable in 40 healthy adult men. Participants receive either the active eye drops or a placebo, and researchers monitor for side effects and how the drug behaves in the body. This is a first step toward possibly devel…

This study tested whether CAM-101 eye drops are safe and can help relieve dry eye in people who developed the condition after a bone marrow transplant (graft-versus-host disease). 64 adults received either a low or high dose of CAM-101 or a placebo drop four times a day for six w…

This study tested whether a dietary supplement called Nutritears, containing lutein, zeaxanthin, curcuminoids, and vitamin D3, can improve dry eye symptoms. 131 adults with dry eye syndrome took either the supplement or a placebo daily for 8 weeks. Researchers measured tear produ…

This study tested two ways to warm the eyelids for people with dry eyes caused by meibomian gland dysfunction. Fifteen adults used a USB-powered warm compress and a self-heating eye mask for two weeks each. Both devices improved tear stability and comfort, but the USB-powered ver…

This study tested whether electroacupuncture (a type of acupuncture with mild electric pulses) can improve symptoms of mild-to-moderate dry eye. 168 adults received either real or sham electroacupuncture. Researchers measured tear film stability and other eye health markers to se…

This study tested an eye drop called HBM9036 in 577 Chinese adults with moderate to severe dry eye. The goal was to see if it reduces eye surface damage and improves symptoms better than a placebo. Participants used the drops for about two months, and doctors measured changes in …

This study tested whether scleral lenses treated with a special coating called Hydra-PEG can improve comfort and reduce dryness in people with dry eye. 46 participants wore two types of lenses over several weeks and rated their comfort on a scale. The goal was to see if the coate…

This pilot study tested whether Tixel, a device used to treat wrinkles around the eyes, could also improve dry eye symptoms. 75 adults with mild to moderate wrinkles and dry eye received the standard Tixel treatment. Researchers measured tear film stability and dry eye questionna…

This study tested three different ways to use a medicated eyelid wipe (IVW-1001) for people with dry eye disease. Fifteen adults with dry eye took part. The main goal was to see how safe and tolerable the different dosing techniques were, and how well they improved tear productio…

This early-phase trial tested YM-101 eye drops in 30 adults with dry eye syndrome. Participants received either high or low dose YM-101 plus artificial tears, then switched to placebo after a washout period. The study measured changes in corneal staining, tear break-up time, and …

This study tested if insulin eye drops can safely and effectively treat moderate to severe dry eye disease. 116 adults received either insulin drops, standard cyclosporin drops, or artificial tears (placebo) for 6 months. The main goal was to see if insulin drops improved corneal…

This study tested whether a special yellow-light, anti-glare phone screen could reduce eye strain and dryness caused by using a phone for 2 hours in a dim room. 70 adults with mild nearsightedness took part. Researchers measured tear quality, eye redness, and other signs of eye f…

This Phase 2 study tested three different dosing schedules of Lagricel Ofteno eye drops (sodium hyaluronate 0.4%) in 141 people with mild to moderate dry eye. Participants used the drops either twice, four times, or six times a day. The main goal was to see which schedule best im…

This study tested three different eye drops (Humylub Ofteno PF, Hyabak, and Lagricel Ofteno PF) in 182 people with mild to moderate dry eye. Participants used the drops four times a day for 30 days. The main goal was to see if Humylub was as good as the others at reducing dry eye…

This study tested whether a dietary supplement could improve dry eye symptoms by changing the bacteria in the gut. Twenty adults with dry eye disease took the supplement for 8 weeks. Researchers measured tear production and eye surface health before and after treatment. The goal …

This study tested a new eye treatment called TTAX03 in 74 people with mild to moderate dry eye disease. The goal was to see if it is safe and if it can reduce eye dryness and damage. Participants received either a single dose of TTAX03 or a saline (salt water) control and were ch…

This study tested whether a new eye drop called T2769 works as well as a commonly used one (Vismed Multi) for people with moderate to severe dry eye. 251 adults used the drops for 35 days. The main goal was to see if T2769 could reduce eye surface damage as effectively as Vismed …

This study tested whether giving two types of light therapy (intense pulsed light and low-level light therapy) before laser eye surgery can help prevent dry eyes afterward. 62 people who were already scheduled for laser vision correction took part. The goal was to see if these tr…

This study tested a gentle laser (micropulse) on 30 people with dry eye from meibomian gland dysfunction. The laser targets tiny blood vessels on the eyelid edge to reduce inflammation and improve tear quality. Researchers measured tear stability and symptom scores to see if the …

This study tested a low-level light therapy mask on 98 adults having cataract surgery. The mask was used one week before and one week after surgery to see if it could prevent or reduce dry eye symptoms. Researchers measured dry eye symptoms, tear stability, and eye surface health…

This study tested whether Miebo eye drops (perfluorohexyloctane) can safely and effectively relieve dry eye symptoms in people who wear soft contact lenses. 104 adults used the drops up to four times daily, both before and while wearing their lenses. Researchers measured changes …

This study tested whether Total 30 contact lenses can help people who previously stopped wearing contact lenses because of discomfort or dryness. Sixty adults aged 18 to 40 who had worn reusable lenses for at least a year but quit within the past two years were refitted with Tota…

This Phase 3 study tested SJP-0132 eye drops against placebo in 427 Chinese adults with dry eye disease. Participants used the drops four times daily for 8 weeks. The goal was to see if the drops improve eye surface damage and reduce dryness symptoms.

This study tested whether a device that warms and massages the eyelids (TearCare) works better than prescription eye drops (Restasis) for dry eye disease. 345 adults with dry eye and blocked eyelid glands were randomly assigned to either an in-office TearCare procedure or twice-d…

This study tested Miebo eye drops in 99 adults with dry eye disease. Participants used one drop in each eye four times daily for 14 days. The main goal was to see how much dry eye symptoms improved after one week, measured on a 0-to-100 scale. The study is complete, but results a…

This small pilot study tested the TearCare system, a device that applies heat to the eyelids, in 24 adults with dry eye disease. The goal was to see if it safely improves tear stability and oil gland function compared to a warm compress. Results were measured after one month.

This study tested a device called TearCare against another device, LipiFlow, in 235 adults with dry eye disease caused by blocked oil glands. The goal was to see if TearCare safely improves tear quality and eye comfort. Participants received one treatment session, and researchers…

This study tested whether taking a daily probiotic capsule for 35 days can reduce dry eye symptoms in adults aged 20 to 65 with confirmed dry eye. Researchers measured tear production, tear quality, and eye surface health before and after the treatment. The goal was to see if pro…

This study tested a gentle light treatment (low-level light therapy) given before and after Femto-LASIK eye surgery. 61 adults without prior dry eye received either real light therapy or a sham treatment. Those who got the real treatment had more stable tears and fewer dry eye sy…

This study tested whether adding acupuncture to standard artificial tears helps people with moderate dry eye more than drops alone. 90 adults were randomly assigned to get either artificial tears only or tears plus acupuncture twice a week for five weeks. Researchers measured sym…

This study tested the TearCare system, a device that gently heats the eyelids for 15 minutes followed by manual expression, in 29 adults with dry eye disease. The goal was to see if a single treatment could improve tear film stability and reduce dry eye symptoms over one month. T…

This study looks at how isotretinoin, a vitamin A-based acne medication, affects eye structures and tear production in people with severe cystic acne. Participants receive standard treatment and undergo eye exams, including dry eye tests and advanced imaging, before and during th…

This study looked at 20 adults who wear an artificial eye to see if it causes more dry eye symptoms and damage to the tiny oil glands in the eyelids. Researchers compared the artificial eye side with the healthy eye side using special imaging and questionnaires. The goal was to u…

This completed study looked at 31 people with dry eye to see if measuring corneal sensitivity (how well the eye feels touch) can detect early-stage neurotrophic keratopathy, a condition where the cornea loses sensation. Researchers aimed to find out which dry eye patients might l…