DRY EYE

This study tests a small device that attaches to a smartphone to help diagnose dry eye disease. It takes special pictures of the eye's surface using different lights. The goal is to see if people can use it at home to get accurate results, compared to a standard eye exam. About 5…

This study tests lifitegrast eye drops (Xiidra) in 30 adults with dry eye disease. Researchers will use a special microscope to see if the drops reduce immune cells on the eye's surface. The goal is to understand how the treatment works, not to cure the condition.

This early-stage study tests a new eye ointment called RC017 in 24 healthy adults to see if it is safe and how the body handles it. The ointment is being developed to treat dry eye disease. Participants will receive either the ointment or a placebo, and researchers will monitor f…

This study tests a special VR headset (Lacrima VR) to see if it can safely improve dry eye symptoms in adults with dry eye disease and meibomian gland dysfunction. Twenty participants will be randomly assigned to receive either the active VR treatment or a sham device with dimmer…

This study looks at whether switching from the dry eye medication Xiidra to a new drop called TRYPTYR (acoltremon 0.003%) can improve symptoms and tear production. About 100 adults who have used Xiidra for at least a month and still have dry eye symptoms will be enrolled. Researc…

This study compares three different eye drops to see which one reduces discomfort after cataract surgery. Researchers will watch 300 adults and measure dryness and tear quality. The goal is to find the most effective drop for easing dry eye symptoms after the procedure.

This study looks at whether switching from Restasis to a new eye drop called TRYPTYR (acoltremon 0.003%) can better improve dry eye symptoms and tear production. About 100 adults who have used Restasis for at least a month but are unhappy with its results will take part. Research…

This study tests whether adding sodium hyaluronate (a moisturizer found in many artificial tears) to autologous serum eye drops (drops made from a patient's own blood) provides better relief for moderate-to-severe dry eye disease. About 20 adults with dry eye from conditions like…

This study looks at how blinking patterns are linked to tear film stability in adults aged 18 to 65, both with and without dry eye symptoms. Participants will answer a questionnaire, have their vision checked, and complete non-invasive blink tasks. The goal is to better understan…

This study follows up with 220 adults who previously took part in the SICCA study at the University of Pennsylvania. Researchers will collect samples like tears, saliva, and blood, along with clinical exams, to learn more about dry eye and Sjögren's syndrome. The goal is to bette…