Researchers track dry eye and Sjögren's over time in Follow-Up study

NCT ID NCT05056012

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study follows up with 220 people who previously took part in the Sjögren's International Clinical Collaborative Alliance (SICCA) study at the University of Pennsylvania. Researchers will collect tears, saliva, blood, and other samples, along with eye and mouth exams, to track changes in dry eye and Sjögren's syndrome over time. The goal is to better understand these conditions, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could improve understanding of how dry eye and Sjögren's syndrome progress, potentially guiding future diagnostic or treatment approaches.
What could go wrong
This is an observational follow-up study, not a treatment trial. It will not directly test any new therapy, and results may not lead to immediate clinical changes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Scheie Eye Institute

    Philadelphia, Pennsylvania, 19104, United States

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Other studies related to the condition(s) this trial covers.