New eye drops aim to soothe dry eye in bone marrow transplant patients
NCT ID NCT03414645
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether CAM-101 eye drops are safe and can help relieve dry eye in people who developed the condition after a bone marrow transplant (graft-versus-host disease). 64 adults received either a low or high dose of CAM-101 or a placebo drop four times a day for six weeks. The main focus was on safety, but researchers also looked for signs of symptom improvement.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
CAM-101 (fibrinogen-depleted human platelet lysate) eye drops
What this could lead to
If successful, this could lead to a new treatment option for dry eye in people with graft-versus-host disease, easing discomfort and improving eye health.
What could go wrong
This is an early-phase trial with only 64 participants, so results may not apply to everyone. The main goal is safety, not proof of effectiveness.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Byers Eye Institute of Stanford University
Palo Alto, California, 94303, United States
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Duke University Eye Center
Durham, North Carolina, 27710, United States
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Massachusetts Eye and Ear Infirmary
Boston, Massachusetts, 02114, United States
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Oregon Health Sciences University - Casey Eye Institute
Portland, Oregon, 97239, United States
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University of Michigan - Kellogg Clinical Research Center
Ann Arbor, Michigan, 48105, United States
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University of Minnesota
Minneapolis, Minnesota, 55455, United States