DIABETIC MACULAR EDEMA

This study tested an experimental drug called vamikibart (RO7200220) given as an eye injection for people with diabetic macular edema, a condition where diabetes causes swelling in the back of the eye and blurs vision. About 394 participants received either the new drug or an act…

This study tested a new eye medication called PRO-169 against a standard treatment (ranibizumab) for diabetic macular edema, a condition that causes vision loss in people with diabetes. 510 adults with diabetes received injections into the eye over one year. The goal was to see i…

This study checked the safety of aflibercept eye injections in 100 Indian adults with diabetic macular edema (DME), a diabetes complication that causes vision loss. Participants received injections every 4 weeks for 5 months, then every 8 weeks for a total of 48 weeks. The main g…

This study tested whether OCS 01 eye drops can improve vision in people with diabetic macular edema, a condition where fluid builds up in the eye due to diabetes. About 400 participants used either the eye drop or a placebo. The main goal was to see if the drops help people read …

This study tested whether adding a new drug (RO7200220) to the standard treatment (ranibizumab) works better than standard treatment alone for people with diabetic macular edema, a condition that causes vision loss. About 187 participants received injections into the eye over 76 …

This study looked at how much of the drug aflibercept gets into the blood when a high dose (8 mg) is injected into both eyes of people with diabetic macular edema or wet age-related macular degeneration. Fifty-one adults received the injections and had blood samples taken to meas…

This study looked at the long-term safety of faricimab, an eye injection, in people with diabetic macular edema (DME), a condition that can cause vision loss. Over 1,400 patients who had completed earlier studies received personalized treatment schedules. The main goal was to tra…

This study tested an experimental oral medication called RZ402 in 94 adults with diabetic macular edema (DME), a condition that causes vision loss in people with diabetes. The goal was to see if the drug is safe and can reduce swelling in the retina and improve eyesight compared …

This study tested two types of eye injections—steroid (Ozurdex) and anti-VEGF—given before cataract surgery to 16 adults with diabetic macular edema (DME). The goal was to see which better controlled retinal swelling and preserved vision after surgery. Participants were followed …

This study tested whether a higher dose (8 mg) of the drug aflibercept, given every 16 weeks, works as well as the standard dose (2 mg) given every 8 weeks for Chinese patients with diabetic macular edema (DME), a diabetes-related eye condition that causes vision problems. About …

This study tested a new treatment called OXU-001, which delivers dexamethasone (a steroid) into a specific layer of the eye using a special device, for people with diabetic macular edema (swelling in the back of the eye due to diabetes). It compared two different doses of OXU-001…

This study tested whether OCS-01 eye drops can improve vision in people with diabetic macular edema, a condition where fluid builds up in the eye due to diabetes. The trial involved 552 participants and compared the eye drops to a placebo. The main goal was to see if the drops he…

This study tested an experimental drug called AG-73305, given as an eye injection, in 25 adults with diabetic macular edema (DME), a condition that causes vision loss in people with diabetes. The goal was to see if the drug is safe and can improve vision and reduce retinal swelli…

This study tested the safety and effectiveness of brolucizumab eye injections in 66 adults with diabetic macular edema, a condition that causes vision loss in people with diabetes. Participants received injections over 40 weeks to see if their vision improved and to track any sid…

This study measured the thickness of the conjunctiva and Tenon's capsule (parts of the eye) in 736 people with neovascular age-related macular degeneration or diabetic macular edema, and in healthy volunteers of similar age. Researchers used a special imaging device (SD-OCT) to t…

This study looked at whether special eye scans can help predict which treatment will work best for people with diabetic macular edema, a common cause of vision loss in diabetes. Researchers analyzed scans from up to 150 participants to find patterns linked to good or poor treatme…