New eye injection shows promise for diabetic vision loss

NCT ID NCT05697809

Completed Disease control Sponsor: Oxular Limited Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 2 trial tested a new way to deliver dexamethasone directly to the back of the eye using tiny microspheres (OXU-001) compared to the standard Ozurdex implant. The study enrolled only 3 adults with diabetic macular edema to check safety and how well the treatment is tolerated. The goal is to see if this new method can provide longer-lasting relief with fewer side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: dexamethasone microspheres (OXU-001)
What this could lead to: If successful, this could offer a longer-lasting treatment option for diabetic macular edema with fewer injections.
What could go wrong: This is a very small early-phase trial (only 3 participants) focused on safety, so efficacy is not yet established. The new delivery method may carry risks like eye inflammation or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetic macular edema Edema eye disorder macular degeneration Macular Edema retinal degeneration retinal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETIC MACULAR EDEMA

Contacts and locations

Locations

Blue Ocean Clinical Research West

Clearwater, Florida, 33761, United States
Emmanuelli Research and Development Center, LLC

Arecibo, 00612, Puerto Rico
Retina Consultants of Minnesota

Minneapolis, Minnesota, 55337, United States
Retina Consultants of Texas

Houston, Texas, 77380, United States
Retinal Consultants of Texas - San Antonio

San Antonio, Texas, 78240, United States
Retinal Research Institute, LLC

Phoenix, Arizona, 85053, United States
Sierra Eye Associates

Reno, Nevada, 89502, United States
University Retina and Macula Associates

Oak Forest, Illinois, 60452, United States
Valley Retina Institute, PA

McAllen, Texas, 78503, United States

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