DIABETIC MACULAR EDEMA

This study is testing whether an oral medication called tonabersat can reduce swelling in the retina (diabetic macular edema) in people who still have good vision. About 128 adults with type 1 or 2 diabetes will take either the drug or a placebo pill for 6 months to see if it thi…

This study is monitoring the safety and effectiveness of brolucizumab, an eye injection, for diabetic macular edema (DME) in a real-world setting. It involves 63 adult patients in India who have vision problems due to DME and are already scheduled to receive this treatment. Resea…

This early-stage study is testing the safety and effects of a new drug called ASKG712, given as an injection into the eye, for people with diabetic macular edema (DME). DME is a swelling in the back of the eye that can cause vision loss in people with diabetes. The main goal is t…

This is an early-stage study to check the safety and side effects of a new drug called RO7497372, given as an injection into the eye, for people with diabetic macular edema (DME). The study has two parts: first to find safe dose levels, and second to test two selected doses more …

This study is observing the long-term safety and effectiveness of the OZURDEX eye implant in patients with diabetic macular edema (DME) in China. The implant slowly releases medication to reduce swelling in the retina. About 110 patients who are already prescribed OZURDEX by thei…

This study is testing whether OCS-01 eye drops can safely reduce swelling in the retina and improve vision for people with diabetic macular edema. The trial involves 552 participants and compares the eye drops to a placebo over 52 weeks. The goal is to find a non-invasive treatme…

This study follows patients with diabetic macular edema (DME), a vision-threatening eye swelling, who didn't respond well to standard anti-VEGF injections. Doctors will observe how these patients do when switched to a slow-release steroid implant (DEX-I) in their regular clinical…

This study is testing a one-time gene therapy injection (called 4D-150) for adults with diabetic macular edema, a condition that causes swelling and vision loss. The goal is to see if this single treatment can safely reduce the need for the frequent eye injections patients curren…

This study is testing if a higher dose (8 mg) of an eye injection called aflibercept can treat diabetic macular edema (DME) as effectively as the standard lower dose (2 mg), but with fewer injections needed. About 333 Chinese adults with DME will receive injections either every 8…

This study is testing a higher dose of an existing eye injection medicine (aflibercept 8 mg) for people with wet age-related macular degeneration (AMD) or diabetic macular edema (DME). It aims to see if this higher dose is safe and effective when given as often as once a month. T…

This study is testing how well the eye injection faricimab works and how safe it is for people with diabetic macular edema (DME), a swelling in the back of the eye that can cause vision loss. It focuses on enrolling adults from racial and ethnic groups that are often underreprese…

This study is testing whether OCS 01 eye drops can safely improve vision in people with diabetic macular edema, a common cause of vision loss in diabetes. About 401 participants will use either the active eye drops or a placebo (vehicle) solution twice daily for a year. Researche…

This study is testing if a new, more proactive schedule for a steroid eye implant works better for diabetic macular edema, a common cause of vision loss. It aims to see if starting with two close-together injections, followed by injections only as needed, leads to greater vision …

This study aims to collect long-term, real-world information on how patients with serious eye conditions like macular degeneration and diabetic eye swelling respond to specific Roche eye injection treatments. It will observe 6,000 patients already receiving these approved treatme…