DEPRESSIVE DISORDER

This study tested a special therapy (OPT-A) for teens aged 10-17 who have both a substance use problem and a mood or anxiety disorder. 140 teens took part. The therapy aims to reduce drug use and improve mental health. Early results suggest it works better than standard care.

This study tested a program called iDOVE2 for teens at risk of peer violence and depression. The program started with a brief session in the emergency department, followed by automated text messages. Researchers aimed to see if this approach could reduce violent behavior and depr…

This study tested a 6-week school program designed to prevent anxiety and depression in American Indian children. 28 children in grades 3-6 from a tribal reservation took part. The program was adapted to include local culture and traditions. Researchers measured changes in anxiet…

This study tested whether a blend of online therapy sessions and a smartphone app could help adults with major depression as much as traditional face-to-face therapy. 105 French adults participated, and researchers measured their depression symptoms using standard questionnaires.…

This study tested a group version of a therapy program for 15 teenagers with severe anxiety or depression in a Spanish day hospital. The program aimed to help teens manage their emotions and reduce symptoms. Researchers checked how teens felt before, right after, and 3, 6, and 12…

This study tested whether an optimized multichannel tDCS device can better ease depression symptoms compared to standard or sham (fake) tDCS. Sixty adults with moderate-to-severe major depression received one of the three tDCS types. Researchers measured mood changes using standa…

This study looked at whether a daily probiotic drink (like Yakult) can reduce cold symptoms in triathletes. 80 healthy adult triathletes drank either the probiotic or a placebo before and after a competition. Researchers tracked symptoms like sore throat and stuffy nose, and meas…

This study tested a non-invasive brain stimulation technique called HD-tDCS in 57 adults with depression. The goal was to see if it could reduce physical symptoms like aches and fatigue, which are common in depression. Participants received either real or fake stimulation, and th…

This study tested whether a mobile app could help reduce anxiety and depression in adults who are already receiving medication for opioid use disorder. 63 participants used the app or continued their usual care for 4 weeks. The goal was to see if the app was easy to use and could…

This study tested an internet-based cognitive behavioral therapy (CBT) program called AMTE for teens with anxiety and depression. Sixty adolescents participated, with half receiving the online therapy and the other half an active control. The program aimed to reduce symptoms of b…

This study tested a non-invasive brain stimulation technique called HD-tACS in 60 adults with depression who had suicidal thoughts. The goal was to see if it could reduce those thoughts and understand how it works in the brain using MRI and EEG. The treatment is a gentle electric…

This pilot study tested a 10-session behavioral activation program delivered via teletherapy to increase physical activity and reduce depressive symptoms in 65 adults aged 18-64 with moderate-to-severe depression. Participants used a smartphone and Fitbit to track activity. The s…

This study tested whether a program called PRISM (Promoting Resilience in Stress Management) is practical and helpful for young adults aged 18-39 who have cancer or desmoid tumors and feel depressed or anxious. The program teaches skills to manage stress and emotions. Researchers…

This study tested if unlimited text-based therapy works better than once-a-week therapy for adults with depression. Over 1,100 participants received either unlimited messaging or weekly sessions with a therapist. The goal was to see which approach improves mood and daily function…

This study tested a brief mental health program called Problem Management Plus (PM+) for adults with depression or anxiety at a primary care clinic in Chile. 56 participants were randomly assigned to either PM+ or their usual care. The goal was to see if the program was practical…

This study tested whether taking part in art activities (like painting, music, or dance) can improve mental well-being and reduce symptoms of anxiety and depression. 382 people with mental health issues were randomly assigned to either an art program or a waitlist. The researcher…

This study tested whether using a person's genetic information (DNA) to select antidepressant medication can improve depression and anxiety in cancer patients. 99 adults with cancer and mild to severe depression or anxiety were randomly assigned to either DNA-guided drug selectio…

This study tested a new, non-invasive light therapy for major depression. 50 adults received either real or fake light treatment on their foreheads three times a week for six weeks. The goal was to see if the light could improve mood and brain function. Researchers measured depre…

This study tested a 16-week group therapy program for Spanish adolescents (ages 11-17) with anxiety or depression. The program taught skills to manage difficult emotions and reduce avoidance behaviors. Researchers measured changes in symptoms and daily functioning over a full yea…

This study looked at the temporary out-of-body or confused feelings some people get when taking Esketamine for depression. Researchers interviewed 15 patients to understand these strange experiences better. The goal was to learn more about this side effect so doctors can find way…

This study tested a new artificial intelligence tool called CBTpro that helps therapists improve their skills in cognitive behavioral therapy for psychosis (CBTp). Over 600 adults with conditions like schizophrenia, bipolar disorder, or severe depression took part. The goal was t…

This study tested whether an Instagram channel called 'ich bin alles' could help teenagers learn more about depression, reduce stigma, and encourage them to seek help. 170 teens who already used Instagram took part. The study measured changes in their knowledge and attitudes, but…

This study looked at how the COVID-19 pandemic affected the mental health of nursing home staff in Occitanie, France. Over 500 workers answered surveys about post-traumatic stress, depression, and burnout. The goal was to understand how common these problems were during the healt…

This study followed 1,290 adults with type 1 or type 2 diabetes for two years to see how mental health issues like depression, anxiety, and eating problems relate to blood sugar control. Participants completed surveys, interviews, and used smartphone apps and glucose monitors. Th…

This study tested whether alerting police officers that a person has a serious mental illness during a routine check can reduce arrests and help them stay in treatment. About 1,400 adults with conditions like schizophrenia, bipolar disorder, or major depression who had been arres…

This study examined blood samples from 300 people to see if depression is linked to faster cell aging. Researchers measured telomere length and stress levels in white blood cells. The goal was to find genetic markers that could help doctors better understand the severity and phys…

This study looked at how young people feel about depression education shared on Instagram. Researchers showed 18 teens (some with depression, some without) posts from the 'ich bin alles' channel and asked what they thought. The goal was to understand if social media can be a help…