DEPRESSIVE DISORDER
Clinical trials for DEPRESSIVE DISORDER explained in plain language.
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Can a social-skills group boost standard therapy for depression and anxiety?
Symptom relief OngoingThis study compares standard cognitive behavioral therapy (CBT) alone to CBT plus a group program called Kiesler Circle Training (KCT) that focuses on improving interpersonal skills. Researchers want to see if adding KCT helps people with depression or anxiety disorders interact …
Matched conditions: DEPRESSIVE DISORDER
Phase: NA • Sponsor: Charite University, Berlin, Germany • Aim: Symptom relief
Last updated May 17, 2026 13:01 UTC
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Vitamin d pills tested as depression aid in Long-Term study
Symptom relief OngoingThis study looks at whether taking vitamin D supplements for six months can help people with depression feel better. Researchers will compare a low dose (10 micrograms) to a high dose (100 micrograms) and track participants for up to 6 years. The goal is to see if vitamin D impro…
Matched conditions: DEPRESSIVE DISORDER
Phase: NA • Sponsor: Kuopio University Hospital • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Could nicotine patches lift depression in seniors?
Symptom relief OngoingThis study looks at whether nicotine patches can improve mood and thinking in older adults (60+) with depression. Participants who completed a previous blinded trial will receive nicotine patches for up to 12 weeks. The goal is to see if the patches are safe and help with depress…
Matched conditions: DEPRESSIVE DISORDER
Phase: PHASE2 • Sponsor: Vanderbilt University Medical Center • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New combo therapy targets tough depression with brain zaps and mindfulness
Symptom relief OngoingThis study tests a new approach for people with depression that hasn't improved with standard treatments. It combines a type of brain stimulation called iTBS with digital mindfulness training to help improve mood and thinking skills. About 70 adults with moderate-to-severe depres…
Matched conditions: DEPRESSIVE DISORDER
Phase: PHASE2 • Sponsor: University of California, San Diego • Aim: Symptom relief
Last updated May 11, 2026 20:38 UTC
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4,000 RA patients get heart scans to uncover hidden risks
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows 4,000 people with rheumatoid arthritis (ages 50-75) over 10 years to learn more about their risk for heart disease, lung problems, and mental health issues. Participants get a special heart CT scan, lung tests, and questionnaires. The goal is to better identify…
Matched conditions: DEPRESSIVE DISORDER
Sponsor: Ellen Margrethe Hauge • Aim: Knowledge-focused
Last updated May 17, 2026 13:06 UTC
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Can placing therapists in pediatric clinics fix the youth mental health crisis?
Knowledge-focused ENROLLING_BY_INVITATIONThis research studies a program that puts social workers in children's primary care clinics across Indiana to provide quick mental health support. The goal is to see if this approach helps more kids get diagnosed and treated early for issues like anxiety, depression, and behavior…
Matched conditions: DEPRESSIVE DISORDER
Sponsor: Indiana University • Aim: Knowledge-focused
Last updated May 17, 2026 13:03 UTC
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Texas launches massive youth mental health study
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to create a registry of 5,000 young people (ages 8-20) with depression or suicidal thoughts across Texas. Researchers will collect data to better understand these conditions and develop models to predict outcomes. The goal is to improve care and support for affect…
Matched conditions: DEPRESSIVE DISORDER
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 12:46 UTC
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Which therapy works best for troubled teens? new study aims to find out
Knowledge-focused ENROLLING_BY_INVITATIONThis study will follow 192 teenagers aged 12 to 20 who are already receiving either Cognitive Behavioral Therapy (CBT) or Brief Strategic Therapy (BST) for conditions like anxiety, depression, or OCD. Researchers will track their progress using questionnaires and interviews over …
Matched conditions: DEPRESSIVE DISORDER
Sponsor: IRCCS Centro Neurolesi Bonino Pulejo • Aim: Knowledge-focused
Last updated May 15, 2026 11:52 UTC
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Can a personalized therapy method work in everyday mental health care?
Knowledge-focused OngoingThis study explores whether a therapy method called Process-based Therapy is practical in real mental health clinics. About 40 adults with depression or anxiety will try this approach, which focuses on each person's unique needs. Researchers will measure how satisfied patients an…
Matched conditions: DEPRESSIVE DISORDER
Phase: NA • Sponsor: Goethe University • Aim: Knowledge-focused
Last updated May 12, 2026 13:43 UTC