Vitamin d pills tested as depression booster in Long-Term study

NCT ID NCT02521012

Ongoing Symptom relief Sponsor: Kuopio University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether taking vitamin D supplements for six months can improve depression symptoms. About 319 adults with depression are getting either a low or high dose of vitamin D daily, while continuing their usual treatment. Researchers will track their mood and health for up to 6 years to see if vitamin D makes a lasting difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Vitamin D (as a dietary supplement)
What this could lead to: If it works, this could point toward vitamin D as a simple, low-cost add-on to improve depression treatment outcomes.
What could go wrong: This is a follow-up of an earlier trial, and the results are not yet published. Vitamin D may not significantly improve depression beyond standard care, and high doses could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Depression depressive disorder endogenous depression

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSION DEPRESSIVE DISORDER

Contacts and locations

Locations

Welbeing Servivces County of North Savo, Kuopio University Hospital, Department of Psychiatry

Kuopio, Finland

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