Vitamin d pills tested as depression booster in Long-Term study
NCT ID NCT02521012
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study looks at whether taking vitamin D supplements for six months can improve depression symptoms. About 319 adults with depression are getting either a low or high dose of vitamin D daily, while continuing their usual treatment. Researchers will track their mood and health for up to 6 years to see if vitamin D makes a lasting difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vitamin D (as a dietary supplement)
What this could lead to
If it works, this could point toward vitamin D as a simple, low-cost add-on to improve depression treatment outcomes.
What could go wrong
This is a follow-up of an earlier trial, and the results are not yet published. Vitamin D may not significantly improve depression beyond standard care, and high doses could have side effects.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Welbeing Servivces County of North Savo, Kuopio University Hospital, Department of Psychiatry
Kuopio, Finland