Scientists probe Esketamine's Mind-Altering side effects

NCT ID NCT06133309

Completed Knowledge-focused Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This study looked at 15 people with depression who experienced temporary dissociative states (feeling disconnected from reality) while taking Esketamine. Researchers used interviews to understand these experiences better. The goal is to learn more about this side effect to improve treatment strategies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Esketamine
What this could lead to: If successful, this could help doctors better understand and manage the dissociative side effects of Esketamine, potentially improving treatment for depression.
What could go wrong: This is a very small, completed study (15 people) that only observes and describes experiences. It does not test a new treatment, so it may not lead to direct changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DEPRESSIVE DISORDER

Contacts and locations

Locations

Centre Hospitalier Intercommunal Toulon La Seyne sur Mer

Toulon, Var, 83100, France

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Other studies related to the condition(s) this trial covers.