Centre Hospitalier Intercommunal De Toulon La Seyne Sur Mer

This study tests a new drug called repotrectinib in 30 frail or elderly patients with advanced lung cancer that has a specific genetic change (ROS1). The goal is to see if the drug can shrink tumors and be well-tolerated in this group, who are often left out of other trials. Part…

This study tests whether repeatedly inflating and deflating a blood pressure cuff on a patient's leg soon after a cardiac arrest can reduce brain damage. The approach, called remote ischemic post-conditioning (RIPOST), aims to protect the brain from injury caused by blood flow re…

This study tests whether lightweight, 3D-printed cutlery handles customized to each patient's hand can help elderly people with neurodegenerative diseases eat more independently. About 75 hospitalized patients will try handles of different sizes, and researchers will measure chan…

This study tests if a new tool called a dual-flow arthroscopy sheath can replace the traditional tourniquet during ACL knee surgery. The goal is to see if it leads to less pain and faster recovery. About 128 adults having their first ACL reconstruction will take part.

This study tests whether platelet-rich plasma (PRP) injections work better than hyaluronic acid (HA) injections for people with advanced knee osteoarthritis (grades III-IV). About 150 adults with knee pain will receive either PRP or HA injections and be followed for up to 12 mont…

This study aims to describe moral injury—a deep conflict between professional values and workplace reality—among 3,073 French healthcare workers. Researchers will use surveys to measure moral injury and burnout, then build a model to identify organizational and personal risk fact…

This study aims to establish normal knee rotation values in healthy athletes who play pivot sports like soccer or basketball. By measuring knee rotation and comparing it between both legs, researchers hope to identify athletes at higher risk for ACL injuries. The goal is to use t…

This study looks at a new system called 'med@psy' that helps people with mental health problems see a psychiatrist within 48 hours, instead of going to the emergency room. About 418 adults will take part. Researchers want to see if this faster access leads to better follow-up car…

This study uses artificial intelligence to group patients who have had a pulmonary embolism (a blood clot in the lung) based on their medical information at diagnosis. The goal is to see if these groups have different outcomes six months later, such as recurrence or long-term com…

This study looks at 400 people who have had a first deep vein thrombosis (DVT) in their leg. Researchers want to see if the amount of clot seen on an ultrasound can predict who will develop post-thrombotic syndrome (PTS), a chronic condition causing pain, swelling, and skin chang…

This study looks at whether a brief increase in airway pressure after suctioning can reopen collapsed lung areas and improve lung volume in ICU patients on ventilators. About 32 adults will be randomly assigned to receive either suctioning alone or suctioning followed by a recrui…

This study looks at whether exercising the arm that isn't in a sling can help keep muscle strength and size in the arm that had shoulder surgery. About 42 adults having shoulder surgery will be split into three groups: standard care, eccentric training, or concentric training of …

This study looks back at CT scans done on adults in one hospital's emergency department over a year. The goal is to see how many of those scans were truly needed based on official guidelines or if they changed how the patient was treated. By understanding overuse, doctors hope to…

This study looks at what happens to eye pressure right after a larger-volume injection of Aflibercept (0.07 mL) for macular diseases like AMD. Researchers will also check if repeated injections cause any long-term changes to the optic nerve over 12 months. About 100 adults who ne…

This study looks at how often sleep apnea occurs in people with peripheral artery disease (PAD), a condition where leg arteries become narrowed. Researchers will monitor 295 adults with PAD using a sleep test called polygraphy. The goal is to better understand the connection betw…

This study looks at whether a non-invasive breathing test called rhinomanometry can reliably tell if someone with a stuffy nose needs surgery. About 200 adults scheduled for nasal surgery will take the test, and researchers will compare the results with standard exams. The goal i…

This study is testing a special care program for adults with obesity. The program offers coordinated support and education to help patients become more active in their own care. Researchers want to see if this approach improves patients' sense of self-efficacy—their belief in the…

This study aims to understand how often, how badly, and why young elite rugby players get hurt. Researchers will track about 400 male and female players (ages ~13-18) from a top French club over two full seasons. They will analyze existing medical records to identify patterns and…