Centre Hospitalier Intercommunal De Toulon La Seyne Sur Mer

This study tests whether repeatedly inflating and deflating a blood pressure cuff on a leg can reduce brain damage in people who survive a cardiac arrest outside the hospital. The procedure, called remote ischemic post-conditioning (RIPOST), is started within 4 hours after the he…

This study tests a drug called repotrectinib in 30 frail or elderly patients with advanced lung cancer that has a specific genetic change (ROS1). The goal is to see if the drug can shrink tumors or stop them from growing. Participants take the drug by mouth, and doctors monitor t…

This study tests whether custom 3D-printed cutlery handles can help people with neurodegenerative diseases eat more independently. 75 patients in rehabilitation care will try handles in different sizes, designed to fit their grip. Researchers will measure changes in eating abilit…

This study tests whether a new tool called a dual-flow arthroscopy sheath can replace the standard thigh tourniquet during ACL knee surgery. The goal is to see if it reduces pain and speeds up recovery. About 128 adults having their first ACL reconstruction will be randomly assig…

This study tests whether injections of platelet-rich plasma (PRP) work better than hyaluronic acid (HA) for people with advanced knee osteoarthritis (grades III or IV). 150 participants will receive three injections of either PRP or HA and be followed for a year. The goal is to s…

This study looks at whether a brief increase in airway pressure (called a recruitment maneuver) after suctioning helps restore lung volume in ICU patients on ventilators. About 32 adults will be enrolled, and each will act as their own control, receiving both the maneuver and no …

This study tracks eye pressure in 100 people receiving a larger-volume injection of Aflibercept (0.07mL) for macular diseases like age-related macular degeneration. Researchers measure pressure right after the injection and at several time points, then check for any nerve damage …

This study compares two ways to help adults with mental health issues get follow-up care. One group gets usual care after an emergency room visit, while the other uses a new system that books a psychiatrist appointment within 48 hours through their general doctor. Researchers wil…

This study looks at whether training the arm that isn't in a sling can help preserve muscle strength and size in the immobilized arm after shoulder surgery. 42 adults undergoing shoulder surgery will be split into three groups: standard rehab, eccentric training, or concentric tr…

This study aims to describe moral injury—a deep conflict between professional values and workplace reality—among 3,073 healthcare workers in France. Researchers will use surveys to measure moral injury and identify organizational and personal risk factors. The goal is to guide sy…

This study uses artificial intelligence to group patients who have had a pulmonary embolism (a blood clot in the lung) based on their medical information at diagnosis. Researchers will track 2,500 patients for 6 months to see how different groups recover. The goal is to help doct…

This study looks at whether a special care pathway for obesity helps patients feel more capable of managing their condition. About 133 adults with obesity will fill out questionnaires on self-efficacy, quality of life, and mood, and some will join focus groups. The goal is to see…

This study aims to establish normal knee rotation values in healthy athletes who play pivot sports like soccer or basketball. Researchers will measure knee rotation in 482 athletes using a device called DYNEELAX. The goal is to better understand what is normal, so doctors can ide…

This study looks at 400 people with a first-time deep vein thrombosis (DVT) in the leg. Researchers want to see if the amount of clot seen on an ultrasound can predict who will develop post-thrombotic syndrome (PTS), a condition causing long-term leg pain, swelling, and skin chan…

This study looks at how often sleep apnea occurs in people with peripheral artery disease (blocked leg arteries). Researchers will monitor 295 adults with leg artery disease using a sleep test. The goal is to better understand the connection between these two conditions, which ma…

This study looks at whether a simple, non-invasive breathing test called rhinomanometry can reliably confirm the need for nasal surgery in people with nasal obstruction. Researchers will compare the test results with standard methods like questionnaires and exams in 200 adults sc…

This study follows about 400 young rugby players (ages 12-18) from Rugby Club Toulonnais over two seasons. Researchers will record every injury that needs medical care, noting how often injuries happen, how serious they are, and what types occur. The goal is to understand injury …