DELIRIUM

This study tested whether early cognitive training and rehabilitation can improve long-term thinking skills in older adults (65+) who experienced delirium during a hospital stay. 283 participants were randomly assigned to receive either the cognitive training program or usual car…

This study tested whether it is possible to set personalized blood pressure targets for critically ill patients using a brain oxygen monitor. Sixteen ICU patients on breathing machines or shock medications had their blood pressure adjusted to match individual brain blood flow nee…

This study tested a French version of the Confusion Assessment Method (CAM), a tool to quickly diagnose acute confusion (delirium) in elderly patients. Researchers compared the CAM results with a psychiatrist's diagnosis using standard criteria. The goal was to see how accurate t…

This study tested a Thai version of a simple tool called the Delirium Diagnostic Tool-Provisional (DDT-Pro) to see if it can accurately diagnose delirium in elderly patients with hip fractures. Delirium is a common complication after hip fracture surgery, but current diagnostic m…

This study tested whether giving IV acetaminophen (Tylenol) every 6 hours during and after heart surgery could prevent delirium—sudden confusion—in patients aged 60 and older. Delirium is common after heart surgery and can lead to longer hospital stays and other problems. The tri…

This study tests whether combining two sedatives, dexmedetomidine and esketamine, can lower the chance of delirium (sudden confusion) in older patients (60+) after surgery in the ICU. Delirium is common and can lead to worse outcomes. The trial will involve 100 participants and t…

This study tested whether the sedative dexmedetomidine can reduce how long non-intubated ICU patients experience agitated delirium. Researchers randomly gave 168 patients either dexmedetomidine or a placebo. The goal was to see if the drug shortens agitation and delirium, and red…

This study tested whether giving a low-dose sedative called dexmedetomidine at night can prevent delirium (sudden confusion) in older adults after heart surgery. The trial involved 504 patients aged 60-89 who had heart surgery with a heart-lung machine. The drug was infused overn…

This study gave robotic pets (like the Joy for All™ cat or dog) to 106 older adults with mild-to-moderate dementia during their hospital stay. The goal was to see if the pets could lower delirium risk, reduce falls, and cut down on strong medications. Researchers compared these p…

This study tested whether weighted blankets can help prevent or reduce delirium in adult ICU patients. 49 participants used the blankets, and researchers measured satisfaction from patients, their families, and healthcare providers. The goal was to see if this simple, non-drug ap…

This study tested whether giving intravenous guanfacine to critically ill patients with delirium in the ICU could improve their brain function. 46 adults on breathing machines or for shock were randomly assigned to receive guanfacine or a placebo. Researchers measured days withou…

This study tested whether therapeutic touch — a gentle, non-invasive technique — can reduce pain, delirium, and improve sleep in 80 intensive care patients. Researchers measured pain, sedation, sleep quality, and vital signs like blood pressure and heart rate. The goal was to see…

This study looked at whether adding dexmedetomidine to standard morphine pain relief after cancer surgery could lower the chance of delirium (sudden confusion) in patients aged 65 and older. A total of 1500 participants were randomly assigned to receive either morphine alone or m…

This study tested a wearable eye-tracking device called EyeControl-Pro in 160 older, ventilated ICU patients. The device lets patients communicate by moving their eyes, which may help reduce delirium—a state of confusion common in intensive care. Researchers compared patients who…

This study tested whether music therapy can prevent hospital-related confusion (delirium) in people with Parkinson's disease or Lewy body dementia. 30 hospitalized adults took part, receiving either music therapy sessions, self-directed music listening, or standard care. Research…

This study tested whether a virtual reality game called ReCognitionVR could help older adults (60+) stay mentally alert after abdominal surgery. Thirty participants used the VR headset or standard orientation methods. The goal was to see if the VR approach is safe, acceptable, an…

This study tested whether early cognitive stimulation—simple mental exercises like orientation, attention, and memory tasks—can reduce delirium in critically ill patients. 130 adults in the ICU were enrolled within 24 hours of admission. The goal was to see if these exercises low…

This study observed 100 adults having planned heart surgery to see how many develop delirium (sudden confusion) and whether a standard risk score called EuroSCORE II could predict it. Researchers checked patients for delirium using a special test. The goal was to better understan…

This study tested whether a device that measures pupil changes (automated pupillometry) can help assess pain in intensive care patients who are confused or delirious after surgery. Pain is hard to evaluate in these patients because they cannot communicate clearly. The study enrol…

This small study tested whether a nurse-led walking and sit-to-stand program is practical and liked by older adults with cognitive issues like dementia who are in transitional care after a hospital stay. Six people took part, and the researchers measured how many joined, stayed, …

This study tested a training program for emergency department staff to better detect delirium—a sudden confusion—in older adults. Researchers trained nurses and doctors at three hospitals and checked if detection improved. About 3,000 patients were involved. The goal was to see i…

This study looked at 73 trauma patients in the ICU to see if brainwave (EEG) patterns could predict delirium before it happens. Researchers recorded brain activity over several days and used machine learning to find early warning signs. The goal is to help doctors spot brain prob…

This study looked at whether hearing and vision loss are linked to delirium (sudden confusion) in older hospital patients. Over 1,500 participants answered screening questions and had their hearing and vision tested. In a smaller trial, researchers tested if posting communication…

This study looked at whether adding a brain wave monitor (pEEG) to standard sedation checks helps reduce delirium and time on a breathing machine in ICU patients. Researchers followed 150 adults on ventilators who needed sedation. They compared those who got both the brain monito…

This study tested a training program to help emergency department nurses better detect delirium in older adults. Delirium, a sudden confusion, affects up to 20% of older ER patients and is often missed. The program trained nurse champions through workshops and telehealth sessions…

This study tested a two-step process to improve care for older adults in the emergency department. First, quick screening tests for fall risk, delirium, and frailty were used. Patients with concerning results were then placed in an observation unit for a full team assessment by g…

This study reviewed medical records of 274 adults who had emergency surgery for a torn aorta (aortic dissection). Researchers looked at how often patients had brain complications like stroke or coma after surgery and whether those complications led to longer stays in the intensiv…

This pilot study tested whether remote smartphone tests of thinking, memory, and motor function can identify older adults who may be vulnerable to cognitive problems after spine surgery. 34 participants completed the tests before surgery, and researchers tracked who developed pos…

This pilot study tested whether keeping blood pressure within a range that ensures good blood flow to the brain during surgery is feasible and safe compared to usual care. Researchers enrolled 27 older adults having hip, knee, or lung surgery. They measured how often blood pressu…