Brain oxygen monitoring guides blood pressure in ICU pilot

NCT ID NCT07296029

Completed Disease control Sponsor: Queen's University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether it is possible to set personalized blood pressure targets for critically ill patients using a brain oxygen monitor. Sixteen ICU patients on breathing machines or shock medications had their blood pressure adjusted to match individual brain blood flow needs. The goal was to see if this approach could reduce delirium and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: norepinephrine and labetalol (blood pressure medications)
What this could lead to: If successful, this approach could lead to better recovery and less delirium for ICU patients by tailoring blood pressure to individual needs.
What could go wrong: This is a very small pilot study (16 people) testing feasibility, not effectiveness. The approach may not improve outcomes or could be impractical in routine care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CRITICAL ILLNESS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Critical Illness delirium respiratory failure Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CRITICAL ILLNESS DELIRIUM RESPIRATORY FAILURE SHOCK

Contacts and locations

Locations

Kingston Health Sciences Center

Kingston, Ontario, K7L 2V7, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.