Brain oxygen monitoring guides blood pressure in ICU pilot

NCT ID NCT07296029

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether it is possible to set personalized blood pressure targets for critically ill patients using a brain oxygen monitor. Sixteen ICU patients on breathing machines or shock medications had their blood pressure adjusted to match individual brain blood flow needs. The goal was to see if this approach could reduce delirium and improve recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

norepinephrine and labetalol (blood pressure medications)

What this could lead to

If successful, this approach could lead to better recovery and less delirium for ICU patients by tailoring blood pressure to individual needs.

What could go wrong

This is a very small pilot study (16 people) testing feasibility, not effectiveness. The approach may not improve outcomes or could be impractical in routine care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Critical Illness delirium respiratory failure Shock

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Kingston Health Sciences Center

    Kingston, Ontario, K7L 2V7, Canada