DELIRIUM

This study tests whether listening to music (Taiwan-localized or classical) combined with mindful breathing can reduce delirium, pain, and anxiety in ICU patients. Fifty-one adults at risk for delirium will receive the intervention twice daily for five days. Researchers will meas…

This study tests whether combining breathing exercises with progressive muscle relaxation can reduce shortness of breath, anxiety, and delirium in patients recovering from heart surgery. 116 adults will be randomly assigned to either receive these techniques plus standard care, o…

This study tests whether a non-invasive brain stimulation technique called TMS can shorten the duration of delirium (sudden confusion) that often occurs after heart surgery in people aged 50 and older. Half of the 144 participants will receive real TMS, and half will receive a sh…

This study tests whether a medication called dexmedetomidine can help patients in the intensive care unit (ICU) sleep more restfully. Good sleep is important for recovery, but ICU conditions often disrupt it. About 50 adult ICU patients will either receive the medication or a pla…

This study tests a portable exercise bike that clamps to hospital beds, allowing patients to pedal their arms and legs while lying down. The goal is to see if using the bike for at least 15 minutes a day can help prevent muscle loss, weakness, and other problems like blood clots …

This early-stage study will test whether an injection of gastrodin, a compound from a traditional Chinese herb, is safe and tolerable in 54 healthy adults. Researchers will also measure how the drug moves through the body. If successful, this could lead to larger studies in patie…

This study tests whether a sleep medication called lemborexant can help older adults in the intensive care unit (ICU) sleep better and reduce their risk of delirium, a state of sudden confusion. The trial will involve 100 patients aged 65 and older who are in the surgical ICU. Pa…

This study compares two sedatives, remimazolam and midazolam, to see which one causes less confusion (delirium) after heart valve surgery in people aged 65 and older. Delirium affects up to 70% of older heart surgery patients and can lead to longer hospital stays and memory probl…

This study compares an AI-powered orientation program to one given by human nurses for patients in the intensive care unit (ICU). The goal is to see if the AI program helps patients have more days without delirium, lowers anxiety and depression, and shortens their hospital stay. …

This study watches brain activity in 300 adults during high-risk surgeries like heart or spine operations. Researchers use special monitors to track brain waves and pressure, linking them to patient outcomes. The goal is to understand why some people develop confusion or brain in…

Delirium is common in hospital intensive care units (ICUs) and can be hard to diagnose. This study will use non-contact cameras to analyze patients' facial micro-expressions and other biological signals. By combining this data with machine learning, researchers aim to build a mod…