COPD

This study is testing if adding a pill called erdosteine to standard COPD inhaler therapy can help control the disease by reducing harmful inflammation and oxidative stress in the lungs. It will involve 30 adults with moderate to severe COPD who are already on stable inhaler trea…

This study is testing if a 20-week program of diet and exercise can help people who have both COPD and obesity. It will measure if the program improves how far they can walk, their lung function, and reduces body-wide inflammation. The goal is to see if managing weight can be a h…

This study is testing whether a new medical device called the Targeted Lung Denervation (TLD) catheter can help people with moderate to severe COPD breathe easier and have fewer serious flare-ups. Researchers will compare the real procedure to a sham (fake) procedure in 300 parti…

This study is testing if a detailed half-day health check can help people with COPD who have frequent, serious flare-ups. The check-up aims to ensure they are on the right COPD treatments, look for other hidden health problems, and create a personal plan. The goal is to reduce th…

This study is testing whether an inhaled medication called iloprost is safe and effective for treating high blood pressure in the lungs of adults with severe COPD. Researchers want to see if the drug lowers pressure in the lung's blood vessels and helps people walk farther. Fifte…

This study is testing a new implantable device called an Artificial Bronchus to help adults with severe emphysema. The device is designed to reduce the amount of trapped air in the lungs, which could help patients breathe more easily and improve their quality of life. Researchers…

This study is testing whether using a non-invasive breathing machine (BiPAP) at home can help people with severe COPD. It will involve 40 patients who have recently been discharged from the hospital and still have high carbon dioxide levels in their blood. Researchers will check …

This study is testing whether a gentle, non-invasive brain stimulation technique can improve thinking skills like memory and attention in people with COPD who also have cognitive impairment. Researchers will compare real brain stimulation to fake (sham) stimulation in 24 particip…

This study is testing whether a pharmacist-guided mobile game can help adults aged 50+ with COPD better manage their condition. Participants will use the game at home for two weeks to learn about their disease, practice inhaler technique, and get medication reminders. The goal is…

This study is testing a new automatic oxygen delivery device called MoblO2 for people with COPD or interstitial lung disease who need oxygen during activity. The device uses a pulse oximeter to automatically adjust oxygen flow to keep blood oxygen at safe levels, aiming to reduce…

This study is testing whether a small breathing device can help Veterans with COPD get better results from their pulmonary rehab program. Researchers will compare the real device to a fake one to see if it helps people improve their shortness of breath, walking ability, and quali…

This study is testing if a simple breathing exercise can help people with COPD feel less anxious and recover better after a bronchoscopy, a common lung exam. Researchers will teach 64 patients a pursed-lip breathing technique right after the procedure to see if it lowers their he…

This study will compare two different breathing training devices to see which one works better for people with COPD. Researchers want to find out if the Breather device or a standard incentive spirometer is more effective at reducing shortness of breath and improving quality of l…

This study is testing a 3-month rehabilitation program for people with COPD. The program combines hospital sessions with exercises done at home. Researchers want to see if this tailored approach helps patients walk farther, breathe easier, and feel better in their daily lives.

This study is testing whether using a whiteboard at a patient's bedside can help reduce feelings of anxiety and depression in people hospitalized with COPD, a serious lung disease. It will also see if the whiteboard improves how satisfied patients are with their nursing care. The…

This study aims to see if measuring certain proteins in the blood can help doctors predict how severe a COPD flare-up will be. Researchers will enroll 75 adults hospitalized for a COPD attack. They will check blood levels of a lung protein and other inflammation markers to see if…

This study is testing whether a special ultrasound technique can measure how hard someone is working to breathe, without needing to insert a tube down their throat. Researchers will compare the ultrasound measurements against the current standard method (which uses a tube) in bot…

This research study aims to understand how the body's immune cells behave differently in people with various lung diseases like asthma, COPD, and pneumonia. Researchers will analyze a single blood sample from 100 participants to look for patterns in how certain white blood cells …

This study aims to collect real-world information from 3000 people with COPD who experience frequent flare-ups. It will track their disease course, treatments, and quality of life over time to better understand patient and caregiver experiences. The goal is to gather knowledge to…

This study aims to find out how many people hospitalized for a COPD flare-up also have hidden heart or kidney problems. Researchers will screen 150 patients in Hong Kong for these conditions at discharge and provide a care package with follow-up. The goal is to understand the ris…

This study aims to understand what goes wrong inside the lungs of people with Chronic Obstructive Pulmonary Disease (COPD). Researchers will analyze lung tissue samples from 150 people who had lung surgery, comparing those with COPD to those without. The goal is to create a detai…

This study aims to create a reliable Turkish version of a questionnaire that helps spot dysfunctional breathing patterns in people with stable COPD. Researchers will translate the questionnaire and then test it on 90 Turkish-speaking adults with COPD to see if it works well and g…

This study aims to understand how different types of exercise affect oxygen levels in the brain and leg muscles of people with COPD. Researchers will use special light sensors to measure these oxygen changes in 60 participants during walking, strengthening, and breathing exercise…

This study aims to understand which breathing test best matches how patients with asthma or COPD feel after using their inhaler. Researchers will compare standard breathing tests with a newer, easier test to see which one better reflects symptom relief. The goal is to improve how…