COPD

This study tests whether a structured care program (called a transition bundle) helps people with COPD recover better after a serious flare-up. The program includes guided steps and regular check-ins. About 1,368 patients across 36 hospitals will take part. The goal is to see if …

This study tests whether atorvastatin, a widely used cholesterol medication, can reduce inflammation and prevent flare-ups in smokers with chronic obstructive pulmonary disease (COPD). About 460 participants will receive either atorvastatin or a placebo for several months. The go…

This study tests whether using a handheld breathing device (OPEP) at home, combined with aerobic exercise, can reduce serious flare-ups and hospital visits in people with moderate to severe COPD. About 312 participants aged 40-80 will be split into four groups: standard care, OPE…

This study tests whether regular follow-up calls or visits from a nurse can help smokers aged 35-65 who are screened for COPD to quit smoking. About 233 participants will receive ongoing nursing support. The goal is to see if this simple, low-cost approach reduces the number of c…

This study looks at 150 adults with COPD who have just had a breathing tube removed. It compares two ways to help them breathe: a high-flow nasal cannula (a soft tube that delivers warm, moist oxygen) versus noninvasive ventilation (a mask that pushes air into the lungs). The goa…

This study tests a new nurse-led counselling program designed to help people with stable COPD manage emotional distress. Fifteen outpatients will receive ten counselling sessions over three months. The main goal is to see if the program is feasible, not to prove it works. Researc…

This study tests an 8-week program called Step-CBT that combines physical activity goals with cognitive behavioral therapy for veterans with COPD who also have depression or anxiety. The program is delivered via video calls to make it accessible. Researchers want to see if it is …

This study is testing whether taking probiotic capsules daily for 16 weeks can reduce shortness of breath and improve lung function in people with COPD. Sixty adults with stable COPD will receive either the probiotic or a placebo. Researchers will measure changes in breathing, sy…

This study follows 200 adults aged 30-55 who smoke or have early COPD to learn how the disease progresses. Researchers will use breathing tests, symptom surveys, and CT scans to find early warning signs. The goal is to better understand risk factors and improve future care for CO…

This study will follow 3,000 people with COPD who have frequent flare-ups to see how the disease changes over time and what treatments they receive. Researchers will collect information from medical records and surveys to understand treatment patterns, quality of life, and caregi…

This large real-world study will follow 10,000 Italian patients with COPD to see how their treatments, flare-ups, and other health conditions affect their risk of death. Researchers will collect data on medications, lung function, and heart problems over time. The goal is to bett…

This study uses special MRI scans with inhaled gases to see how lungs work in people with asthma, COPD, or COVID-19. Researchers will follow up to 160 participants over several years to track changes in lung function. The goal is to better understand why some patients struggle wi…

This study looks at 1,600 adults in Hong Kong who have been diagnosed with asthma or COPD to find out how many have both conditions (called Asthma-COPD Overlap). Researchers will track their health for 3 years to see how they do and whether their treatment matches guidelines. The…

This study looks at whether a structured exercise and education program (pulmonary rehabilitation) can reduce inflammation and oxidative stress in people with stable COPD. Researchers will measure specific blood markers before and after the program in 27 adults aged 40-80. The go…

This study aims to improve how doctors communicate with patients facing serious illnesses like cancer, heart failure, COPD, or dementia. Researchers will give doctors detailed feedback on their conversations about goals of care. The goal is to help patients receive care that matc…

This study is refining a questionnaire to help doctors detect small airway dysfunction in people with COPD. Researchers will also compare two breathing tests (spirometry and oscillometry) to see which works better in primary care. About 108 adults with asthma, COPD, or both will …

This study aimed to use a special MRI technique with hyperpolarized xenon gas to see how lung function changes in people with COPD after a procedure called targeted lung denervation. The goal was to better understand how the treatment affects breathing. However, the study was wit…

This study tests a wearable device called the RESP™ Biosensor that listens to lung sounds and chest movements. It is designed to help monitor people with COPD after they leave the hospital. The goal is to see if the device can detect early signs of a COPD flare-up, so patients ca…

This study is testing a tiny camera called micro OCT that can take detailed pictures of cells inside the lungs and nose. Researchers want to see if it works well in people with cystic fibrosis and other lung conditions. The goal is to eventually use this imaging to detect early d…

This study aims to find COPD earlier in people who are already getting a lung CT scan as part of a lung health check. Researchers will invite 568 current or former smokers to take a simple breathing test a few weeks after their CT scan. The goal is to see if this approach helps d…

This study follows nearly 3,000 people with COPD (a chronic lung disease) over several years to understand how the disease progresses and what factors influence it. Researchers measure lung function, analyze mucus, and track environmental exposures like air pollution. The goal is…