Could probiotics be a breath of fresh air for COPD?

NCT ID NCT07339280

ENROLLING_BY_INVITATION Symptom relief Sponsor: University Hospital of Split Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether taking probiotic capsules daily for 16 weeks can reduce shortness of breath and improve lung function in people with COPD. Sixty adults with stable COPD will receive either the probiotic or a placebo. Researchers will measure changes in breathing, symptoms, and inflammation to see if probiotics offer any benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: probiotic supplement (Lactobacillus plantarum and Saccharomyces boulardii)
What this could lead to: If it works, this could point toward a simple, safe way to help people with COPD breathe easier and feel better day-to-day.
What could go wrong: This is a small, early-stage trial with only 60 people. Probiotics may not improve COPD symptoms, and results might not apply to everyone with the disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE) PROBIOTIC PROBIOTIC SUPPLEMENT

Contacts and locations

Locations

General Hospital Karlovac

Karlovac, Croatia
General Hospital Sibenik

Šibenik, 2200, Croatia
General Hospital Vinkovci

Vinkovci, Croatia
University Hospital Centre Sestre milosrdnice

Zagreb, Croatia
University Hospital Split

Split, 2100, Croatia

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