New biologic drug solrikitug aims to tame COPD inflammation

NCT ID NCT06496620

Ongoing Disease control Sponsor: Uniquity One (UNI) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 2 times

Summary

This Phase 2 trial tests solrikitug, a biologic drug given as a shot, in 171 adults with moderate-to-severe COPD and high eosinophil levels. The study compares two doses of solrikitug against a placebo to see if it safely reduces inflammation and improves lung function over time. Researchers will measure changes in blood eosinophil counts and breathing tests to determine if the drug helps control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Solrikitug (a biologic drug given as a shot under the skin)
What this could lead to: If it works, solrikitug could become a new treatment option to help control COPD by reducing inflammation and improving lung function.
What could go wrong: This is an early Phase 2 trial with only 171 people, so results may not apply to everyone. The drug may not work better than placebo, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD

Contacts and locations

Locations

ADP Clinical Research

Splendora, Texas, 77372, United States
Accellacare Wilmington

Wilmington, North Carolina, 28401, United States
Access Research Institute

Brooksville, Florida, 34613, United States
Advanced Respiratory and Sleep Medicine

Huntersville, North Carolina, 28078, United States
Allergy and Clinical Immunology Associates

Pittsburgh, Pennsylvania, 15241, United States
Alliance for Multispecialty Research

Tempe, Arizona, 85281, United States
Alpine Research Organization, Inc.

Layton, Utah, 84041, United States
AnMed Health

Anderson, South Carolina, 29621, United States
Antelope Valley Clinical Trials

Lancaster, California, 93534, United States
Appalachian Clinical Research, LLC

Adairsville, Georgia, 30103, United States
AppleMed Research Group, LLC

Miami, Florida, 33126, United States
Ark Clinical Research - Ballinger

Long Beach, California, 90815, United States
Axsendo Clinical Research

Houston, Texas, 77030, United States
Bradford Teaching Hospitals NHS Foundation Trust

Bradford, BD9 6RJ, United Kingdom
CPCC - Research, LLC

East Point, Georgia, 30344, United States
Care Access - Shreveport

Shreveport, Louisiana, 71105, United States
Centricity Research

Rincon, Georgia, 31326, United States
Certified Research Associates Finger Lakes Medical Research, LLC

Cortland, New York, 13045, United States
Clinical Research Associates of Central PA

DuBois, Pennsylvania, 15801, United States
Clinical Research of Gastonia

Gastonia, North Carolina, 28054, United States
Clinical Research of Rock Hill

Rock Hill, South Carolina, 29732, United States
Clinical Research of West Florida - Clearwater

Clearwater, Florida, 33765, United States
Clinical Research of West Florida - Tampa

Tampa, Florida, 33606, United States
Coral Research Clinic Corporation

Miami, Florida, 33186, United States
Corning Center for Clinical Research Smith Allergy & Asthma Specialists

Horseheads, New York, 14845, United States
De La Cruz Research Center, LLC

Miami, Florida, 33184, United States
Direct Helper Research Center

Hialeah, Florida, 33012, United States
Downtown LA Research Center, Inc.

Los Angeles, California, 90017, United States
Epic Medical Research-Surprise

Sun City, Arizona, 85351, United States
Florida Institute for Clinical Research

Orlando, Florida, 32825, United States
Gulf Coast Clinical Research

Houston, Texas, 77070, United States
Henderson Trials

Henderson, Nevada, 89052, United States
Henry Ford Health System

Detroit, Michigan, 48207, United States
Hillcrest Medical Research, LLC

DeLand, Florida, 32720, United States
Homestead Associates in Research Inc.

Homestead, Florida, 33033, United States
Indiana Medical Research Institute

Merrillville, Indiana, 46410, United States
Innovative Research of West Florida, Inc.

Clearwater, Florida, 33756, United States
IntraCare Clinical

Greenville, Texas, 75401, United States
IntraCare Health Center

Dallas, Texas, 75254, United States
IntraCare Health Center

McKinney, Texas, 75071, United States
JY Research Institute

Cutler Bay, Florida, 33189, United States
Mayflower Clinical

South Dartmouth, Massachusetts, 02747, United States
Medical University of South Carolina

Charleston, South Carolina, 29245, United States
Midwest Chest Consultants

Saint Charles, Missouri, 63301, United States
Momentum Hawke's Bay

Hastings, 4122, New Zealand
Momentum Kapiti

Waikanae, 5036, New Zealand
Momentum St. Leonards

Sydney, New South Wales, 2065, Australia
Momentum Taringa

Taringa, Brisbane, QLD 4068, Australia
Momentum Tauranga

Tauranga, 3110, New Zealand
Momentum Wellers Hill

Tarragindi, Queensland, 4121, Australia
Momentum Wellington

Mount Cook, Wellington Region, 6021, New Zealand
Montana Medical Research, Inc.

Missoula, Montana, 59808, United States
New Phase Research & Development

Knoxville, Tennessee, 37909, United States
New Zealand Respiratory & Sleep Institute (NZRSI)

Auckland, 1051, New Zealand
Newport Native MD, Inc.

Newport Beach, California, 92663, United States
NexGen Research

Lima, Ohio, 45801, United States
Northside Health

Coffs Harbour, New South Wales, 2450, Australia
Novak Clinical Research

Tucson, Arizona, 85741, United States
OK Clinical Research

Edmond, Oklahoma, 73034, United States
OM Research

Oxnard, California, 93036, United States
OSF HealthCare Saint Francis Medical Center

Peoria, Illinois, 61606, United States
OnSite Clinical Solutions

Charlotte, North Carolina, 28277, United States
Pacific Clinical Research Network Auckland - PCRN Auckland

Auckland, 1024, New Zealand
Pacific Clinical Research Network Auckland - PCRN West Auckland

New Lynn, Auckland, 0600, New Zealand
Peters Medical Research

High Point, North Carolina, 27260, United States
Phoenix Medical Group

Peoria, Arizona, 85381, United States
Premier Research Center, LLC

Hendersonville, Tennessee, 37075, United States
Pro-Care Research Center, Corp.

Miami Gardens, Florida, 33014, United States
Proactive RGV

Brownsville, Texas, 78520, United States
Prospective Research Innovations, Inc.

Rancho Cucamonga, California, 91730, United States
Pulmonary & Sleep Specialists

Dickson, Tennessee, 37055, United States
Pulmonary Research Institute of SE Michigan

Farmington Hills, Michigan, 48336, United States
Pulmonology, Sleep, Asthma, and Allergy Center - Dublin

Dublin, Georgia, 31021, United States
Queen Anne Street Medical Centre

London, W1T 6AH, United Kingdom
R & H Clinical Research

Katy, Texas, 77494, United States
Reliant Medical Research LLC

Miami, Florida, 33165, United States
Remington Davis

Columbus, Ohio, 43215, United States
Revival Research Institute, LLC

Dearborn, Michigan, 48126, United States
Revive Research Institute

Southfield, Michigan, 48075, United States
Rutgers, The State University of New Jersy

New Brunswick, New Jersey, 08901, United States
SMS Clinical Research

Mesquite, Texas, 75149, United States
San Marcus Research Clinic, Inc.

Miami Lakes, Florida, 33014, United States
Sarasota Clinical Research

Sarasota, Florida, 34239, United States
Southeastern Research Center

Winston-Salem, North Carolina, 27103, United States
Syed Research Consultants

Sheffield, Alabama, 35660, United States
TBC Research

Tamarac, Florida, 33321, United States
TTS Research

Boerne, Texas, 78006, United States
Tandem Clinical Research

Metairie, Louisiana, 70006, United States
Temple University

Philadelphia, Pennsylvania, 19140, United States
Ten20 Clinical Research, LLC

Carrollton, Texas, 75010, United States
The Medicines Evaluation Unit, an IQVIA business

Wythenshawe, Manchester, M23 9QZGB, United Kingdom
The Research Group of Lexington, LLC

Lexington, Kentucky, 40503, United States
Triad Clinical Trials

Greensboro, North Carolina, 27410, United States
University of Alabama at Birmingham Hospital

Birmingham, Alabama, 35294, United States
University of Pittsburgh/UPMC

Pittsburgh, Pennsylvania, 15213, United States
Valencia Medical & Research Center

Miami, Florida, 33174, United States
Velocity Clinical Research - Anderson

Anderson, South Carolina, 29621, United States
Velocity Clinical Research - Boise

Meridian, Idaho, 83642, United States
Velocity Clinical Research - Bristol

London, N12 8BU, United Kingdom
Velocity Clinical Research - Columbia

Columbia, South Carolina, 29204, United States
Velocity Clinical Research - Denver

Englewood, Colorado, 80110, United States
Velocity Clinical Research - Gaffney

Gaffney, South Carolina, 29340, United States
Velocity Clinical Research - Grants Pass

Grants Pass, Oregon, 97257, United States
Velocity Clinical Research - Greenville

Greenville, South Carolina, 29615, United States
Velocity Clinical Research - Hampton

Hampton, Virginia, 23666, United States
Velocity Clinical Research - Medford

Medford, Oregon, 97504, United States
Velocity Clinical Research - Spartanburg

Spartanburg, South Carolina, 29303, United States
Velocity Clinical Research - Union

Union, South Carolina, 29379, United States
Velocity Clinical Research High Wycombe

High Wycombe, HP11 2QW, United Kingdom
Y&L Advanced Health Care, Inc.

Miami, Florida, 33144, United States

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