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Could a gentle zap on the face help COPD patients breathe easier?

NCT ID NCT07686302

Not yet recruiting Symptom relief Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This study explores whether a mild electrical stimulation on the face (trigeminal nerve) can reduce the feeling of breathlessness. It first tests the technique in healthy volunteers to understand how it affects breathing control, then checks if it is feasible and helpful for people with COPD. Participants will receive both active stimulation and a sham (fake) version to compare effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Non-invasive trigeminal nerve stimulation (electrical pulses on the face)
What this could lead to
If it works, this could offer a drug-free way to reduce breathlessness in people with COPD, improving daily comfort and activity.
What could go wrong
This is a very early, small study (40 people) testing feasibility and basic effects. The approach may not reduce breathlessness in real-world COPD patients, and some may find the facial stimulation uncomfortable.

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset Dyspnea

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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