Can Mountain-Air rehab loosen stiff COPD airways?
NCT ID NCT07063563
First seen Sep 11, 2026 · Last updated Sep 11, 2026
Summary
Researchers are studying whether a pulmonary rehabilitation program at moderate altitude changes airway resistance in adults with COPD. Participants complete an endurance training cycle, with some sessions using extra oxygen through a nasal tube and others breathing regular room air. The team measures breathing mechanics before and after rehab using a non-invasive test called forced oscillation, and compares results between low and moderate altitude.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pulmonary rehabilitation at moderate altitude, with some training sessions using extra oxygen
- What this could lead to
- If altitude-based rehabilitation changes airway resistance, it could shape how rehab programs for COPD are designed and where they are held.
- What could go wrong
- This is a small study of 52 people, so any changes in breathing measurements may be modest or not hold for other patients. Altitude can also affect oxygen levels, which matters for people with COPD.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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52 people
The number who actually took part.
- Started
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Jul 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Aged ≥18 years * Stable clinical condition for \>3 weeks (e.g., no exacerbations) * Resting SpO₂ ≥88% and exercise-induced hypoxemia defined as a drop in SpO₂ of ≥4% and/or a level below 90% during the 6MWT * Informed consent documented by signature Exclusion Criteria: * Severe daytime resting hypoxemia (SpO₂ \<88%) * Long-term oxygen therapy * Unstable clinical condition requiring adjustment of pharmacological or other treatment modalities, need for intensive care, or presence of relevant severe comorbidities * Inability to comply with study procedures (e.g., due to language barriers, psychological disorders, neurological or orthopedic impairments, walking disability, or inability to ride a bicycle) * Women who are pregnant or breastfeeding * Enrolment in another clinical trial involving active treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Eastern Switzerland University of Applied Sciences
Sankt Gallen, Canton of St. Gallen, 9000, Switzerland
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National center for cardiology and internal medicine
Bishkek, Kyrgyzstan, Kyrgyzstan
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