CONSTIPATION

This study looked at 20 children with Hirschsprung disease, a condition where part of the bowel lacks nerve cells, causing severe constipation. Researchers compared two surgical methods—Swenson and Soave—to see which one had shorter operation time and better daily bowel movement …

This study compared two types of surgery (circular Soave vs. heart-shaped) in 177 children with Hirschsprung's disease, a condition that causes severe constipation. The goal was to see which method leads to better bowel control and fewer complications. Results help doctors choose…

This study tested a drug called isatuximab in 43 people with AL amyloidosis whose disease came back or didn't respond to prior treatments. AL amyloidosis is a rare condition where abnormal proteins build up in organs. Isatuximab is a lab-made antibody that helps the immune system…

This study looked at whether a gentle abdominal massage can help with constipation in people receiving hemodialysis. 49 adults took part, and researchers measured changes in constipation severity and quality of life. The goal was to see if this simple, drug-free approach could of…

This study tested whether a telerehabilitation-based exercise program can reduce constipation symptoms and improve quality of life. It included 32 adults diagnosed with constipation who had fewer than three bowel movements per week and other related symptoms. Participants receive…

This study tested a small, low-volume irrigation device (Qufora IrriSedo MiniGo) in 92 adults with fecal incontinence (stool leakage) or chronic constipation. Participants used the device at home to gently rinse the lower bowel. The main goal was to see if it reduced how much bow…

This study tested whether ear massage can help prevent or reduce constipation after lower extremity surgery. Constipation is very common after such surgeries, affecting up to 94% of patients. The researchers enrolled 40 patients and used ear massage to stimulate bowel activity by…

This study looked at whether giving people a gentle abdominal massage before surgery could help prevent constipation after the operation. Sixty adults who were constipated and scheduled for general surgery took part. Half received the massage, and the other half did not. Research…

This study tested whether applying a magnetic field to the belly (transabdominal magnetic field therapy) can reduce constipation severity in people with long-term constipation. 75 adults were split into three groups: one received the real magnetic therapy twice a week for 8 weeks…

This study tested a special insole designed to relieve constipation in 139 adults receiving palliative care. Participants walked for 20 minutes daily for four weeks, either with or without the insole. Researchers tracked bowel habits and comfort levels to see if the reflexology-b…

This study tested a treatment called posterior tibial nerve stimulation (PTNS) for children aged 8-18 with constipation due to pelvic floor dyssynergia. The treatment uses mild electrical pulses to a nerve in the ankle to improve bowel function. 40 children were randomly assigned…

This study tested a device called MOWOOT for adults with chronic constipation. It compared the device to standard treatment (trans-anal irrigation). The goal was to see if the device improves quality of life and constipation symptoms. 86 adults who had been using standard treatme…

This study looked at whether one session of classical abdominal massage can improve blood vessel stiffness, muscle oxygen levels, and exercise ability in adults with chronic constipation. Thirty participants were randomly assigned to receive either the massage or a placebo (rest …

This study tested whether a probiotic called Weizmannia coagulans BC99 can help relieve chronic constipation by improving gut bacteria. Researchers enrolled 90 Chinese adults with constipation and measured changes in stool form and bowel movement frequency. The goal was to see if…

This study tested whether two different probiotic supplements could improve constipation and weight gain in 30 children with cerebral palsy. Participants took either Lactobacillus reuteri or a prebiotic-enriched Lactobacillus rhamnosus daily for 28 days. Caregivers tracked bowel …

This study looked at whether taking a laxative before surgery can make bowel movements less uncomfortable after pelvic prolapse repair. 74 women having minimally invasive surgery were asked to take a laxative either before and after surgery or only after. The goal was to see if t…

This early-phase study tested a new wireless patch that uses a tiny, painless electrical current to push bowel medications through the skin. The goal was to see if this method is safe and works as well as a wired version. Only 2 healthy volunteers took part, so the results are ve…

This study looked at how two drugs, neostigmine and glycopyrrolate, move through the body when given through an IV or a skin patch using a mild electrical current (iontophoresis). Six healthy adults took part to help researchers understand the drugs' behavior. The goal was to gat…

This study aimed to improve how doctors diagnose chronic constipation and fecal incontinence, which affect about 1 in 4 people. Researchers tested a new device called Fecobionics that combines several tests into one, making diagnosis faster and more reliable. They studied 130 pat…

This study tested a new, faster care pathway for people with chronic constipation at a University of Michigan gastroenterology clinic. Researchers wanted to see how often doctors ordered specific tests and pelvic floor therapy, and how satisfied patients were with their care. 109…

This study tested whether it is possible to treat constipation in people with chronic kidney disease and measure changes in their health. Fourteen adults with both conditions received treatment and were monitored for 6 weeks. The main goal was to see if patients would follow the …