CONSTIPATION

This study tested a new, faster care plan for people with chronic constipation. Researchers wanted to see if using this plan made doctors more likely to order specific tests and physical therapy for the pelvic floor muscles. They tracked 109 patients to see if the new approach im…

This Phase 2 trial tested whether the antibody drug isatuximab could help control AL amyloidosis in patients whose disease had returned or didn't respond to prior treatments. The study enrolled 43 adults with confirmed organ damage from this rare protein disorder. Participants re…

This study compared two different surgical methods, called Swenson and Soave, for treating children with Hirschsprung's disease, a condition where part of the bowel lacks the nerves needed to move stool. The main goal was to see if one technique took less time to perform. Researc…

This study aimed to improve how doctors diagnose chronic constipation and fecal incontinence (bowel control problems). Researchers tested new devices, including a simulated feces device called Fecobionics, on 130 patients with these conditions and 101 healthy volunteers. The goal…

This study tested whether a single session of abdominal massage could provide immediate benefits for people with chronic constipation. Researchers compared 30 participants who received the massage to a group that did not, measuring effects on blood vessel stiffness, muscle oxygen…

This early study tested a new wireless skin patch designed to deliver medication without needles. The goal is to help people with spinal cord injuries who suffer from severe constipation and bowel incontinence. Researchers checked if the patch was safe and if the body absorbed th…

This study tested whether a guided exercise and education program delivered online could help relieve constipation symptoms and improve quality of life. Researchers enrolled 32 adults with chronic constipation to participate in the remote program. The goal was to see if this conv…

This study tested if a gentle electrical stimulation to a nerve near the ankle could help children with severe constipation caused by uncoordinated pelvic floor muscles. Researchers compared the real stimulation to a fake (sham) treatment in 40 children aged 8-18. The goal was to…

This study tested whether a daily probiotic supplement could help relieve chronic constipation. 90 adults with long-term constipation took either the probiotic or a placebo pill for a period of time. Researchers measured changes in bowel movements and stool consistency to see if …

This study tested whether starting a laxative before pelvic organ prolapse surgery helps reduce discomfort with bowel movements after the operation. Researchers compared women who took the laxative both before and after surgery to those who only took it afterward. The goal was to…

This study tested if a simple ear massage could help relieve constipation in patients recovering from leg surgery. Researchers compared 40 patients who received the massage to those who did not, measuring how quickly normal bowel activity returned. The goal was to see if this non…

This study tested whether a special insole, designed using reflexology principles, could help manage constipation in people receiving palliative care. For four weeks, one group of patients walked for 20 minutes a day wearing the insoles, while another group walked without them. R…

This study tested whether daily probiotic supplements could help children with cerebral palsy who suffer from chronic constipation. For 28 days, children took either a Lactobacillus reuteri supplement, a Lactobacillus rhamnosus supplement with a prebiotic, or received standard ca…

This study tested whether abdominal massage could help relieve constipation in people receiving hemodialysis treatment for kidney failure. Researchers compared 24 patients who received a 15-minute massage twice a week for six weeks during their dialysis sessions with 25 patients …

This small pilot study tested whether treating constipation in people with chronic kidney disease might improve their kidney health. Researchers gave 14 patients with both conditions a constipation treatment and checked if it was practical to deliver. They measured changes in kid…

This early study tested how two drugs used for bowel problems in people with spinal cord injuries get into the body. Researchers compared giving the drugs through a standard IV to delivering them through a special skin patch. The goal was to see if the patch method could be a fut…