Could a simple constipation treatment protect your kidneys?

NCT ID NCT06123195

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small pilot study looked at whether treating constipation with a common laxative (lactulose) is practical for people with chronic kidney disease. Fourteen participants took lactulose daily for up to 6 weeks. The main goal was to see if people would stick with the treatment and complete the study. Researchers also checked for changes in kidney function and blood markers. The study was completed, but results are not yet reported.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lactulose

What this could lead to

If successful, this could show that treating constipation is a safe and practical way to possibly improve kidney health in patients with chronic kidney disease.

What could go wrong

This is a very small pilot study with only 14 people, so results may not apply to everyone. It only tests feasibility, not whether constipation treatment actually improves kidney outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome constipation disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Memphis VA Medical Center

    Memphis, Tennessee, 38104, United States