Could a simple constipation treatment protect your kidneys?

NCT ID NCT06123195

Completed Symptom relief Sponsor: University of Tennessee Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small pilot study looked at whether treating constipation with a common laxative (lactulose) is practical for people with chronic kidney disease. Fourteen participants took lactulose daily for up to 6 weeks. The main goal was to see if people would stick with the treatment and complete the study. Researchers also checked for changes in kidney function and blood markers. The study was completed, but results are not yet reported.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lactulose
What this could lead to: If successful, this could show that treating constipation is a safe and practical way to possibly improve kidney health in patients with chronic kidney disease.
What could go wrong: This is a very small pilot study with only 14 people, so results may not apply to everyone. It only tests feasibility, not whether constipation treatment actually improves kidney outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome constipation disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC KIDNEY DISEASE CONSTIPATION

Contacts and locations

Locations

Memphis VA Medical Center

Memphis, Tennessee, 38104, United States

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