New constipation drug tested in young and elderly volunteers

NCT ID NCT01655771

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage study tested a single dose of TD-1211, an experimental drug for constipation, in 47 healthy adults split into younger (18-45) and older (65-85) groups. Researchers measured how the body absorbs and eliminates the drug and checked for side effects. The goal was to see if age affects drug safety and processing, not to test if it works for constipation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TD-1211

What this could lead to

If successful, this study could help determine safe dosing of TD-1211 for constipation in different age groups.

What could go wrong

This is an early Phase 1 trial in healthy volunteers, not patients. It only measures safety and drug levels, not whether the drug works for constipation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

constipation disorder Opioid-Induced Constipation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ICON Development Solutions

    San Antonio, Texas, 78209, United States