Gut bacteria booster may relieve constipation without drugs
NCT ID NCT06761443
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This trial tests whether a probiotic called Pediococcus acidilactici PA53 can improve stool consistency, gut bacteria balance, and inflammation in adults with functional constipation. Participants take the probiotic or a placebo daily for 8 weeks. The study measures changes in stool form, digestive symptoms, and markers of immune response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a probiotic supplement containing Pediococcus acidilactici PA53
- What this could lead to
- If it works, this could point toward a natural, non-drug option for managing chronic constipation by improving gut health.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to everyone. Probiotics can cause mild digestive upset in some people.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Department of Nutrition, General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Gut bacteria may hold the key to constipation relief