CONSTIPATION

This study aims to improve biofeedback therapy for adults with chronic constipation caused by poor muscle coordination during bowel movements. Researchers will measure how well participants can empty their bowels before and after treatment, and track changes in constipation sympt…

This study is testing a new, more detailed diagnostic tool called high-resolution manometry to better understand severe constipation that doesn't respond to standard laxatives. Researchers will compare measurements from patients with this severe condition to those from healthy vo…

This study is testing whether a specific probiotic supplement can safely help improve bowel movements in adults with chronic constipation. Researchers will compare the probiotic against a placebo (a dummy pill) in 80 participants. The main goal is to see if the probiotic helps sh…

This study is testing which of two common laxative methods works better to prevent painful constipation after pelvic organ prolapse surgery. Researchers will compare an oral medication (senna) with a rectal suppository (bisacodyl) in 88 women having this type of vaginal surgery. …

This study is testing whether a medication called tenapanor, already approved for IBS with constipation, can help relieve constipation in people with cystic fibrosis. Twenty-five participants will take the drug twice daily for four weeks while tracking their bowel movements and s…

This small pilot study is testing whether a specific liquid probiotic drink can improve constipation symptoms and quality of life. It will involve 20 adults who self-report constipation. Researchers will track changes in bowel habits, symptoms, and gut transit time using question…

This study is testing whether a daily probiotic supplement can help relieve constipation and improve gut comfort in healthy, active adults. About 30 participants will take the probiotic and a placebo for separate 4-week periods to see which one works better. Researchers will meas…

This study is testing whether a popular over-the-counter dietary supplement called Inno Cleanse can reduce feelings of bloating in otherwise healthy adults. Researchers will give the supplement or a placebo to 30 participants for two weeks to see if it helps. They will also check…

This study is testing whether an herbal formula called Ma-Zi-Ren-Wan (MZRW) can help relieve constipation in people who have survived cancer. Researchers will compare MZRW to a placebo (a dummy pill) over two weeks to see if it increases comfortable bowel movements. They will als…

This study is testing whether a medication called pyridostigmine can safely and effectively treat chronic constipation in people with Parkinson's disease. Sixteen participants with Parkinson's and significant constipation will take the medication for several weeks while tracking …

This study is testing whether drinking a probiotic milk beverage daily for four weeks can relieve constipation symptoms in Filipino adults. Researchers want to see if it improves stool consistency, how often people go, and reduces stomach discomfort. They will compare a group dri…

This study is testing a new device called Fecobionics to better understand a specific type of chronic constipation called pelvic floor dyssynergia. Researchers will use the device to measure muscle function in 24 patients before, during, and after they receive standard biofeedbac…