Could a nerve drug ease Parkinson's gut troubles?

NCT ID NCT05603715

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether pyridostigmine, a drug that stimulates the gut, can safely relieve chronic constipation in people with Parkinson's disease. Constipation is a common and bothersome symptom that often appears years before movement problems. Sixteen adults with Parkinson's will take the drug for four weeks and record their bowel movements to see if it helps.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Vermont Medical Center

    RECRUITING

    Burlington, Vermont, 05401, United States

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