No-Needle patch could help spinal injury patients poop

NCT ID NCT06351852

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This early study tested a wireless patch that uses a tiny electric current to push two drugs (neostigmine and glycopyrrolate) through the skin and into the blood. The goal is to help people with spinal cord injury have predictable bowel movements without needles. Only 2 healthy volunteers took part, and the study focused on safety and how the drugs enter the body.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Neostigmine and Glycopyrrolate
What this could lead to
If it works, this could lead to a needle-free way for people with spinal cord injury to manage bowel problems at home.
What could go wrong
This is a very early, tiny study in just 2 healthy people. It only checks safety and drug levels, not whether it actually works for bowel problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • James J. Peters Veterans Affairs Medical Center

    The Bronx, New York, 10468, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.