BREAST CARCINOMA

This early-phase trial tested a new drug called SRG-514 in 25 people undergoing breast-conserving surgery for breast cancer. The drug was given directly into the area where the tumor was removed. The main goal was to find a safe dose and check for side effects. This is a first st…

This study tested a new way to give radiation to people with early-stage breast cancer. Instead of many sessions, patients received just three doses aimed only at the tumor area. The goal was to see if this shorter treatment is safe and works well. 77 patients took part, and the …

This study tested a type of breast cancer surgery called nipple-sparing mastectomy, where the breast tissue is removed but the nipple and skin are kept. It involved 450 women with early-stage breast cancer who needed a full mastectomy. The goal was to see if this surgery keeps th…

This study tested a special collagen scaffold placed during breast cancer surgery to help the breast keep its shape after tumor removal. Forty women with early-stage breast cancer took part. The goal was to see if the scaffold safely helps the breast heal and look better, improvi…

This early-stage trial tested whether adding pulsed electromagnetic fields (PEMFs) to standard chemotherapy is safe for people with breast cancer. Fourteen participants received the combination before surgery. The main goal was to check for side effects, not to cure the disease. …

This study tested a new 3D ultrasound called quantitative transmission imaging (QTI) against standard MRI for breast cancer screening in 26 women at high risk. The goal was to see if QTI could effectively detect suspicious findings. If it works, QTI might offer a faster, less exp…

This study tested whether contrast-enhanced ultrasound (CEUS) can estimate the pressure inside breast tumors without using a needle. Twenty-five women scheduled for breast biopsy received an IV contrast agent and underwent ultrasound imaging. The goal was to see if the ultrasound…

This study looked at over 3,000 women with dense breast tissue to see if adding molecular breast imaging (MBI) to standard digital breast tomosynthesis (DBT) finds more invasive cancers. MBI uses a small amount of radioactive material to highlight active cells, like cancer. The g…

This study tested whether contrast-enhanced mammography (CEM) can find more breast cancers than standard mammography in women already diagnosed with breast cancer. 89 women received CEM, which uses an iodine dye to highlight suspicious areas. The goal was to see if CEM detects ad…

This study looked at 157 women with breast cancer who had a mastectomy. It compared two ways to drain fluid after surgery: active drainage (using suction) and passive drainage (gravity). The goal was to see which method led to less fluid buildup (seroma), shorter drain time, and …

This study tested whether bupropion, a medication that affects brain chemicals, can improve low sexual desire in women who have had breast or gynecologic cancer. About 230 women took either bupropion or a placebo pill for 9 weeks. The main goal was to see if their self-reported s…

This study compared two ways to manage pain after a mastectomy: a nerve block (pectoral block) using bupivacaine, and standard IV painkillers (ketorolac). Sixty women undergoing mastectomy for breast cancer took part. The goal was to see which method provides better pain relief i…

This study looked at whether using a special numbing technique (tumescent local anesthesia) during breast cancer surgery leads to less pain afterward compared to standard general anesthesia. 349 women who had breast cancer surgery took part. The goal was to see if this approach c…

This pilot study tested whether a mindfulness program could help prevent chemo-brain in women about to start chemotherapy for breast cancer. Fifteen women participated in mindfulness sessions and underwent brain scans and blood tests. The main goal was to see if women would stick…

This phase 3 trial tested whether adding prochlorperazine or olanzapine to standard anti-nausea medication (netupitant/palonosetron and dexamethasone) better controls nausea and vomiting caused by chemotherapy in breast cancer patients. Over 1,300 women receiving common chemo dru…

This completed study looked at 121 women in Brazil with a certain type of advanced breast cancer (HR+/HER2-). Researchers tracked how doctors prescribed palbociclib combined with other drugs in everyday practice, not in a strict trial setting. The goal was to describe patient bac…

This completed study involved 775 women who had breast-conserving surgery and radiation for breast cancer. Researchers compared different surgery and radiation techniques to see which ones led to less breast hardening (fibrosis) and better cosmetic results. The goal was to find w…

This study looked at whether cancer survivors living in rural areas can create their own survivorship care plans and learn from telehealth education. 261 survivors of breast, colorectal, lung, lymphoma, or prostate cancer took part. The goal was to see if this approach improves t…

This study tested a mobile-friendly app called HERCaRE, designed to help Black women who have finished breast cancer treatment. The app provides culturally tailored education and resources to support survivorship. Researchers measured how often participants used the app and wheth…

This study analyzed blood samples from breast cancer patients to find genetic factors that might predict how well they respond to chemotherapy. Researchers looked at patients who had already received standard chemo drugs. The goal was to identify biomarkers that could guide futur…

This completed study looked at blood and tumor samples from 66 women with breast cancer who were about to receive chemotherapy before surgery. Researchers searched for unique protein patterns that might show whether the tumor would shrink with treatment. The goal was to find a wa…

This study looked at how well women of color understand their personal risk of developing breast cancer. Researchers surveyed 324 women aged 18 to 50 who had never had breast cancer. The goal was to see if their perceived risk matched actual risk, which can help improve education…

This study tested whether breathing in humidified wood or fragrant oils could mimic the immune-boosting effects of a forest walk. 28 adults who finished chemotherapy or radiation for early-stage breast or prostate cancer took part. The goal was to see if this approach is practica…

This observational study enrolled 94 women with breast cancer to see if it's possible to collect blood, stool, and survey data from older patients taking aromatase inhibitors (a type of hormone therapy). The main goal was to test the feasibility of gathering this information for …

This study looked at 120 women with early-stage breast cancer to see if having low muscle mass (sarcopenia) before treatment raises the risk of nerve damage from the chemotherapy drug paclitaxel. Researchers measured muscle mass on CT scans and checked for nerve symptoms using qu…

This study looked at how breast cancer treatments affect sexual health in 25 women. Participants filled out anonymous questionnaires about their sexual function, quality of life, and emotional well-being before and after chemotherapy. The goal was to understand how these factors …

This study looked back at medical records of 517 women in Gulf countries with advanced breast cancer that was previously labeled HER2-negative. Researchers re-tested old tumor samples to find out how many actually have HER2-low breast cancer, a newer subtype. The goal is to bette…

This study tested whether a special MRI sequence called ZTE can show breast biopsy markers made of bone cement more clearly than standard metal markers. Twenty adults with breast cancer had MRI scans, and two radiologists rated how well the markers were seen. The goal is to impro…