BREAST CARCINOMA

This study looks at women with breast cancer that has spread to lymph nodes under the arm, found before surgery. Normally, doctors remove many lymph nodes, which can cause arm swelling and pain. The trial tests if removing only the first few affected nodes is just as effective fo…

This study will develop and test an AI model that combines MRI, ultrasound, digital pathology, and patient data to predict how well breast cancer responds to neoadjuvant therapy. Researchers will analyze data from 1,800 participants across multiple centers. The goal is to help do…

This study tests an artificial intelligence (AI) system that analyzes breast images (digital breast tomosynthesis) to help doctors diagnose breast cancer more accurately. Researchers will train the AI on thousands of images from 5000 women to detect tumors, tell benign from malig…

This study compares two types of nerve blocks given before breast cancer surgery (modified radical mastectomy) to see which one helps patients recover better. Sixty women will receive either a newer block called subtransverse interligamentary plane block or the standard thoracic …

This study collects spinal fluid, blood, saliva, and tumor samples from 139 adults with HER2-positive or triple-negative breast cancer that has spread to other organs but not yet to the brain. Researchers will analyze these samples for tumor DNA that might predict when the cancer…

This study looks at how a special program, called the Geriatric Surgery Verification Program, works at the James Cancer Hospital. The program helps doctors and nurses better care for patients aged 65 and older who need cancer surgery. It includes checking for age-related issues l…

This study surveys 240 breast cancer patients to understand how they use herbs and supplements alongside standard treatments like chemo or hormone therapy. Researchers want to see if ethnicity influences which products people take. The goal is to gather information, not to test a…

This study is testing a new web and mobile app called SHIELD, designed to support women with hormone receptor-positive breast cancer who are on long-term hormone therapy. The goal is to see if the app is easy to use and helpful for managing treatment. About 30 women will particip…

This study looks at whether breast cancer's biology changes when it returns after treatment. Researchers will review medical records of 200 patients treated between 2015 and 2025. The goal is to see how often key markers differ between the first tumor and the recurrence, which co…

This study looks at 100 older women (60+) newly diagnosed with breast cancer to understand how frailty affects their quality of life. Researchers will use geriatric assessments and questionnaires to measure frailty and well-being over 6 months. The goal is to help doctors make be…