Nerve block or IV drugs? study seeks best pain relief after mastectomy

NCT ID NCT07257874

Completed Symptom relief Sponsor: Islamabad Medical and Dental College Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compared two ways to manage pain after a mastectomy: a nerve block (pectoral block) using bupivacaine, and standard IV painkillers (ketorolac). Sixty women undergoing mastectomy for breast cancer took part. The goal was to see which method provides better pain relief in the first 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: bupivacaine (nerve block) and ketorolac (IV painkiller)
What this could lead to: If the nerve block works better, it could become a standard way to manage pain after mastectomy, reducing the need for strong IV painkillers.
What could go wrong: This is a small, single-center study with only 60 participants. The results may not apply to all patients, and nerve blocks carry risks like infection or allergic reaction.

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Conditions

The condition(s) this trial relates to.

breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MASTECTOMY, MODIFIED RADICAL

Contacts and locations

Locations

Akbar Niazi Teaching Hospital

Islamabad, 44000, Pakistan

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Other studies related to the condition(s) this trial covers.