Infective vaginitis

This virtual trial tests whether a daily prebiotic and probiotic supplement can relieve symptoms of bacterial vaginosis and yeast infections, such as itching, odor, and abnormal discharge. Women aged 25 and older with these concerns will take two capsules daily for 30 days. The s…

This trial tests whether taking a specific probiotic supplement (Lactobacillus crispatus Lc-G22) alongside standard antifungal treatment can help prevent repeat vaginal yeast infections. One hundred women with a history of frequent yeast infections will receive either the probiot…

This trial investigates whether taking a postbiotic supplement daily for four weeks can help ease symptoms of vaginal yeast infections in women. Participants are sexually active women with a confirmed yeast infection. The study compares the postbiotic to a placebo to see if it im…

This study compared two common antibiotics—azithromycin (single dose) and doxycycline (7-day course)—for treating anal chlamydia in women who also had a vaginal chlamydia infection. The goal was to see which treatment clears the anal infection better, since anal chlamydia often g…

This study tested whether taking a probiotic called Lactobacillus crispatus LCr86 by mouth could improve vaginal health in women with an intermediate vaginal microbiome. 80 women participated, taking either the probiotic or a placebo for 8 weeks. Researchers measured changes in v…

This study tested the safety of using pHyph, a vaginal tablet that naturally restores acidity, for 12 days in 32 adult women with bacterial vaginosis (BV). BV is a common infection causing unpleasant discharge and odor, and often returns after antibiotic treatment. The goal was t…

This study tested whether vaginal capsules containing live lactobacilli (good bacteria) are safe and tolerable for treating bacterial vaginosis (BV), a common infection. Fifty-seven women with BV took either the lactobacillus capsules or the standard antibiotic metronidazole. The…

This study tested whether vaginal probiotic capsules can cure bacterial vaginosis (BV) better than a placebo. 402 women with BV took part. The main goal was to see if more women were cured 21-30 days after treatment with the probiotic compared to placebo. The trial was completed …

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Over 400 participants took either the study drug or a placebo for 12 weeks after an initial treatment, and…

This study tested whether vaginal capsules containing two types of Lactobacillus probiotics can treat bacterial vaginosis, a common vaginal infection. Sixty-six women received either the probiotic capsule or a placebo. The goal was to see if the probiotics could restore normal va…

This study tested a new oral medication, oteseconazole, to see if it can prevent recurrent yeast infections in women who have had at least three infections in the past year. Participants first received standard treatment for their current infection, then took either oteseconazole…

This study tested a device that uses UVA and blue light to treat bacterial vaginosis and yeast infections. 38 women received one or two light treatments. Researchers checked if symptoms improved and if the vaginal microbiome became healthier. The goal is to find an alternative to…

This study tested two common antibiotics, clindamycin and metronidazole, taken orally for a week to treat abnormal vaginal flora in pregnant women at high risk for preterm labor. The goal was to see which drug better clears the infection and reduces risks like early delivery. 166…

This study tested whether an oral probiotic supplement could help restore healthy bacteria in the vagina. It included 32 women aged 35-43 with vaginal imbalance and fertility concerns. Researchers measured how well the probiotic colonized the body and its effects on immune and an…

This study tested whether adding a vaginal clindamycin cream to standard oral metronidazole works better than oral metronidazole alone for treating bacterial vaginosis. One hundred women with confirmed BV took part. The goal was to see if the combination relieved symptoms like di…

This study tested a gel called Lactal Gel to see how well it treats bacterial vaginosis, a common vaginal infection. Fifty women aged 18 and older used the gel for one week. Doctors checked if the infection cleared and asked about symptoms like odor and itching. The goal was to s…

This study tested a vaginal pessary (Gedea) in 26 women with yeast infections. Participants used the device daily for 6 days. Researchers checked if symptoms like itching and burning went away by day 7 to 14. The goal was to see if the device could safely treat the infection with…

This study tested whether a rapid point-of-care test (Xpert® Xpress MVP) helps doctors diagnose vaginal infections more accurately than usual methods. 351 women with symptoms like discharge or itching were randomly assigned to either usual care or the rapid test. Researchers then…

This study tested whether giving an antibiotic (clindamycin) to pregnant women with bacterial vaginosis (a common vaginal infection) before 13 weeks of pregnancy could lower the chance of very early preterm birth. Over 3,000 pregnant women took part. The goal was to see if early …

This study followed 603 pregnant women in South Africa to see if infections or bacteria in the vagina are linked to how early they give birth. Researchers tested for sexually transmitted infections, yeast, and other germs at the start of pregnancy and again at 30-34 weeks. The go…