Infective vaginitis

This study tests whether a vaginal ovule device, used alongside standard antibiotics or antifungals, improves vaginal health in women with bacterial vaginosis or yeast infections. Eighty women aged 18 to 60 receive either the active device or a placebo ovule over three treatment …

This study tests whether blue LED light therapy can improve symptoms of common vaginal conditions like menopause-related dryness, bacterial vaginosis, and yeast infections. About 150 women aged 18 to 75 will receive the treatment either at home or in a clinic. Researchers will ch…

This study tests a new drug called GenSci142, given as a vaginal capsule, for treating bacterial vaginosis (BV). About 30 women with BV will receive either GenSci142 or a standard antibiotic cream to compare safety and how well each works. The goal is to see if the new capsule is…

This phase 2 trial tests whether transferring vaginal fluid from healthy donors can help women aged 18-25 with recurrent bacterial vaginosis (BV). Participants first receive standard antibiotics, then the transplant. The goal is to see if this restores a healthy vaginal microbiom…

This study tests whether a probiotic called Lactobacillus gasseri KABP®064 can prevent bacterial vaginosis (BV) from returning after standard antibiotic treatment. BV is a common vaginal infection that often comes back within a year. The trial will involve 160 women with a histor…

This study tests whether a probiotic supplement containing Lactobacillus crispatus can reduce the number of times bacterial vaginosis (BV) comes back in women who have had it repeatedly. About 156 women aged 18-45 will take either the probiotic or a placebo daily for 12 weeks aft…

This study tests a new treatment called FB301, a capsule containing beneficial bacteria, for women with an imbalance of vaginal bacteria who have had a failed frozen embryo transfer (IVF). Thirty women aged 18-40 will receive FB301 or a placebo during a mock IVF cycle, with some …

This study tests whether adding a vaginal tablet containing good bacteria and a low-dose hormone (Gynoflor®) to standard preterm labor treatment can help women stay pregnant longer. About 80 pregnant women between 24 and 33 weeks will receive either the tablet or a placebo for 6 …

This early-stage trial tests a new drug called GenSci142 in 30 healthy Chinese women to see if it is safe and how the body processes it. Participants receive a single dose of the drug or a placebo, and are monitored for side effects for 15 days. The goal is to gather safety infor…

This trial tests whether a self-administered vaginal swab, analyzed with advanced molecular technology, can detect and treat bacterial imbalances early in pregnancy. Pregnant women at high risk of preterm birth will either receive this screening plus targeted antibiotics or stand…

This study tests whether BPR-101 capsules, taken with the antibiotic metronidazole, can prevent bacterial vaginosis (BV) from coming back. Eighty women with BV will receive either the active treatment or a placebo. The main goal is to see if the combination lowers the rate of BV …

This study tests a medical device called Rephegyn vaginal ovules to help treat fungal (candidiasis) and bacterial infections. The device is designed to help heal the vaginal lining and reduce symptoms like discharge, pain, and itching. About 34 adults with recurrent infections wi…

This study tests whether point-of-care STI tests, which give results in about 10 minutes, can speed up treatment for pregnant women compared to standard lab tests. About 756 pregnant women at Grady Memorial Hospital will either get the rapid tests or standard testing. The goal is…