Can a vaginal bacteria capsule boost IVF success?
NCT ID NCT07453069
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests a new treatment called FB301, a capsule containing beneficial bacteria, for women with an imbalance of vaginal bacteria who have had a failed frozen embryo transfer (IVF). Thirty women aged 18-40 will receive FB301 or a placebo during a mock IVF cycle, with some also receiving a vaginal cleanse. The goal is to see if FB301 can restore healthy bacteria levels and improve pregnancy outcomes in a subsequent real embryo transfer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
FB301 (a capsule containing live bacteria) and chlorhexidine vaginal cleanse
What this could lead to
If successful, this could lead to a treatment that improves the vaginal bacterial balance, potentially increasing the chance of pregnancy after frozen embryo transfer.
What could go wrong
This is a small early-phase trial with only 30 participants, so results may not apply to everyone. The treatment may not improve pregnancy rates, and there is a risk of side effects from the vaginal cleanse or the bacteria.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for VAGINAL DYSBIOSIS are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Boston IVF
Waltham, Massachusetts, 02451, United States